Yankees vs. Cardinals prediction: Yankees predicted to win Sunday's MLB matchup [8/17/2025]

The St. Louis Cardinals will face the New York Yankees in MLB action at Busch Stadium on Sunday, beginning at 2:15PM ET.

The Cardinals will send Miles Mikolas (6-9, 4.97 ERA) to the mound, while the Yankees are going with Will Warren (7-5, 4.34 ERA).

Based on updated simulations, Dimers' advanced MLB model projects the Yankees as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Yankees-Cardinals game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Yankees with a win probability of 58%, while the Cardinals have 42%."

For further insights into Sunday's matchup, including best bets and picks, visit our interactive Yankees vs. Cardinals predictions page.

Cardinals vs. Yankees prediction: Who will win, cover the run line?

Using trusted machine learning and data, we have simulated the outcome of Sunday's MLB game between the Yankees and Cardinals 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Yankees a 58% chance of beating the Cardinals.

According to our model, the Cardinals (+1.5) have a 54% chance of covering the run line, while the over/under total of 9 runs has a 52% chance of staying under.

Yankees vs. Cardinals odds [8/17/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Yankees	Cardinals
Run Line	-1.5 (+105)	+1.5 (-122)
Moneyline	-158	+140
Total	o9 (+100)	u9 (-120)

All odds are correct at the time of publication and are subject to change.

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Yankees vs. Cardinals picks and best bets

Our model's strongest edge in today's Yankees vs. Cardinals matchup is on the moneyline.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free ⚾️ picks

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Yankees vs. Cardinals game-day updates and essential details

Sunday's MLB game between the Cardinals and Yankees at Busch Stadium is scheduled to commence at 2:15PM ET.

• Who: New York Yankees vs. St. Louis Cardinals
• Date: Sunday, August 17, 2025
• Time: 2:15PM ET/11:15AM PT
• Venue: Busch Stadium

Dimers.com's full preview of Sunday's Yankees vs. Cardinals matchup includes our prediction, picks and the latest betting odds.

Before making any Yankees vs. Cardinals picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Yankees, with a 58% win probability, will likely beat the Cardinals on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Yankees vs. Cardinals insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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