Yankees vs. Angels Prediction: Yankees Predicted to Win Wednesday's MLB Matchup [5/28/2025]

MLB action continues on Wednesday at 9:38PM ET as the New York Yankees lock horns with the Los Angeles Angels at Angel Stadium.

The Angels will start Yusei Kikuchi (1-4, 3.17 ERA), while the Yankees are going with Clarke Schmidt (1-2, 4.58 ERA).

Based on the latest simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Yankees as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's NY Yankees-LA Angels game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Yankees' chance of winning at 56%, with the Angels at 44%."

For a closer look at Wednesday's matchup, including best bets and picks, visit our interactive Yankees vs. Angels predictions page.

Angels vs. Yankees Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data, we have simulated the result of Wednesday's MLB game between the Yankees and Angels 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Yankees a 56% chance of defeating the Angels.

According to our model, the Angels (+1.5) have a 57% chance of covering the run line, while the 8.5-run over/under has a 52% chance of staying under.

Yankees vs. Angels Odds [5/28/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Yankees	Angels
Run Line	-1.5 (+100)	+1.5 (-118)
Moneyline	-160	+140
Total	o8.5 (-108)	u8.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Yankees vs. Angels Picks and Best Bets

Our model's biggest edge in today's Yankees vs. Angels matchup is on the moneyline.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Yankees vs. Angels Game-Day Updates and Essential Details

Wednesday's MLB action between the Angels and Yankees at Angel Stadium is scheduled to commence at 9:38PM ET.

• Who: New York Yankees vs. Los Angeles Angels
• Date: Wednesday, May 28, 2025
• Time: 9:38PM ET/6:38PM PT
• Venue: Angel Stadium

Dimers.com's full preview of Wednesday's Yankees vs. Angels matchup includes our prediction, picks and the latest betting odds.

Before making any NY Yankees vs. LA Angels picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

• Explore how MLB odds work and dive into MLB live betting strategies
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Conclusion

We predict the Yankees, with a 56% win probability, will likely beat the Angels on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Yankees vs. Angels insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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