Yankees vs. Red Sox prediction: Cy Young candidate Max Fried takes on Red Sox today [9/13/2025]

The Boston Red Sox will square off with the New York Yankees in MLB action at Fenway Park on Saturday, beginning at 4:10PM ET.

The Red Sox will start Brayan Bello (11-6, 3.12 ERA), while the Yankees have opted for Cy Young hopeful Max Fried (16-5, 3.02 ERA).

Based on the latest simulation results, Dimers' proven MLB model predicts the Yankees as the most likely winner of today's game.

For further insights into Saturday's matchup, including best bets and picks, visit our interactive Yankees vs. Red Sox predictions page.

Red Sox vs. Yankees prediction: Who will win, cover the run line?

Using powerful machine learning and data analysis, we have simulated the result of Saturday's MLB matchup between the Yankees and Red Sox 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Yankees a 57% chance of defeating the Red Sox.

According to our model, the Red Sox (+1.5) have a 56% chance of covering the run line, while the 9-run over/under has an equal 50-50 chance of hitting.

Yankees vs. Red Sox odds [9/13/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Yankees	Red Sox
Run Line	-1.5 (+108)	+1.5 (-128)
Moneyline	-154	+130
Total	o9 (+101)	u9 (-122)

All odds are correct at the time of publication and are subject to change.

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Yankees vs. Red Sox picks and best bets

Our model's biggest edge in today's Yankees vs. Red Sox matchup is on the run line.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets today

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Yankees vs. Red Sox game-day updates and essential details

Saturday's MLB matchup between the Red Sox and Yankees at Fenway Park is scheduled to start at 4:10PM ET.

• Who: New York Yankees vs. Boston Red Sox
• Date: Saturday, September 13, 2025
• Time: 4:10PM ET/1:10PM PT
• Venue: Fenway Park

Dimers' comprehensive preview of Saturday's Yankees vs. Red Sox matchup includes our prediction, picks and the latest betting odds.

Before making any Yankees vs. Red Sox picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Yankees, with a 57% win probability, will likely beat the Red Sox on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Yankees vs. Red Sox insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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