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Yankees vs. Orioles Prediction: Yankees Predicted to Win Monday's MLB Matchup [4/28/2025]

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Written by Jason Bevilacqua

Our expert prediction for Monday's New York Yankees vs Baltimore Orioles matchup.

New York Yankees-Baltimore Orioles Predictions and Game Preview.
Oriole Park at Camden Yards sets the stage for the MLB matchup between the New York Yankees and Baltimore Orioles this Monday.

The Baltimore Orioles will face the New York Yankees, in what is expected to be a tight MLB game, at Oriole Park at Camden Yards on Monday, starting at 6:35PM ET.

Tomoyuki Sugano (2-1, 3.54 ERA) will be the starting pitcher for the Orioles, while the Yankees have opted for Will Warren (1-0, 4.79 ERA).

Based on the latest simulations, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Yankees as the most likely winner of today's game.

"Our team has utilized the latest data to simulate Monday's NY Yankees-Baltimore game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"Incorporating recent updates and thousands of additional inputs, our prediction shows the Yankees are likely to win, with a probability of 53%, compared to the Orioles' 47%."

For further insights into Monday's matchup, including best bets and picks, visit our interactive Yankees vs. Orioles predictions page.

Orioles vs. Yankees Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and statistical analysis, we have simulated the result of Monday's MLB game between the Yankees and Orioles 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Yankees a 53% chance of beating the Orioles.

According to our model, the Orioles (+1.5) have a 59% chance of covering the run line, while the over/under total of 9.5 runs has a 51% chance of staying under.

 

Yankees vs. Orioles Odds [4/28/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type Yankees Orioles
Run Line -1.5 (+120) +1.5 (-135)
Moneyline -130 +115
Total o9.5 (-102) u9.5 (-108)

All odds are correct at the time of publication and are subject to change.

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Yankees vs. Orioles Picks and Best Bets

Our model's strongest edge in today's Yankees vs. Orioles matchup is on the over/under.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Yankees vs. Orioles Game-Day Updates and Essential Details

Monday's MLB game between the Orioles and Yankees at Oriole Park at Camden Yards is scheduled to commence at 6:35PM ET.

Dimers.com's in-depth preview of Monday's Yankees vs. Orioles matchup includes our prediction, picks and the latest betting odds.

Before making any NY Yankees vs. Baltimore picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

Conclusion

We predict the Yankees, with a 53% win probability, will likely beat the Orioles on Monday.

AI and automation have enhanced this article to quickly deliver accurate Yankees vs. Orioles insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Stay informed with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds offer the latest predictions for the World Series, American League, National League and each division.

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Written by
Jason Bevilacqua
Head of Content and Communities

Jason Bevilacqua, an expert in MLB, NHL, NBA, MLS, and NFL, delivers game previews, best bets, and props. Since 2020, as Head of Social and Community at Dimers, he has contributed insightful articles utilizing data-driven models and simulations.

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