Mets vs. Padres Prediction: San Diego Predicted to Win Monday's MLB Matchup [7/28/2025]

The San Diego Padres will face the New York Mets in MLB action at PETCO Park on Monday, beginning at 9:40PM ET.

The Padres will send Dylan Cease (3-10, 4.59 ERA) to the mound, pitting him against Frankie Montas (3-1, 4.62 ERA) for the Mets.

Based on the latest simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Padres as the most likely winner of today's game.

For a closer look at Monday's matchup, including best bets and picks, visit our interactive Mets vs. Padres predictions page.

Padres vs. Mets Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and statistical analysis, we have simulated the result of Monday's MLB matchup between the Mets and Padres 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Padres a 55% chance of defeating the Mets.

According to our model, the Mets (+1.5) have a 63% chance of covering the run line, while the over/under total of 8 runs has a 51% chance of going over.

Mets vs. Padres Odds [7/28/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Mets	Padres
Run Line	+1.5 (-192)	-1.5 (+165)
Moneyline	+110	-130
Total	o8 (-108)	u8 (-106)

All odds are correct at the time of publication and are subject to change.

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Mets vs. Padres Picks and Best Bets

Our model's biggest edge in today's Mets vs. Padres matchup is on the total.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free MLB Picks

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Mets vs. Padres Game-Day Updates and Essential Details

Monday's MLB game between the Padres and Mets at PETCO Park is scheduled to commence at 9:40PM ET.

• Who: New York Mets vs. San Diego Padres
• Date: Monday, July 28, 2025
• Time: 9:40PM ET/6:40PM PT
• Venue: PETCO Park

Dimers.com's full preview of Monday's Mets vs. Padres matchup includes our prediction, picks and the latest betting odds.

Before making any Mets vs. Padres picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Padres, with a 55% win probability, will likely beat the Mets on Monday.

AI and automation have enhanced this article to quickly deliver accurate Mets vs. Padres insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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