Mets vs. Marlins prediction: Why Mets are favored to win Saturday's MLB matchup [9/27/2025]

The Miami Marlins will square off with the New York Mets in MLB action at loanDepot park on Saturday, starting at 4:10PM ET.

Eury Pérez (7-5, 4.20 ERA) will start for the Marlins, while the Mets will counter with Clay Holmes (11-8, 3.66 ERA).

Based on updated simulations, Dimers' advanced MLB model predicts the Mets as the most likely winner of today's game.

For a closer look at Saturday's matchup, including best bets and picks, visit our interactive Mets vs. Marlins predictions page.

Marlins vs. Mets prediction: Who will win, cover the run line?

Using trusted machine learning and data, we have simulated the result of Saturday's MLB game between the Mets and Marlins 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Mets a 59% chance of defeating the Marlins.

According to our model, the Marlins (+1.5) have a 55% chance of covering the run line, while the over/under total of 8 runs has a 58% chance of going over.

Mets vs. Marlins odds [9/27/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Mets	Marlins
Run Line	-1.5 (+125)	+1.5 (-144)
Moneyline	-140	+120
Total	o8 (-110)	u8 (-108)

All odds are correct at the time of publication and are subject to change.

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Mets vs. Marlins picks and best bets

Our model's biggest edge in today's Mets vs. Marlins matchup is on the run line.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Mets vs. Marlins game-day updates and essential details

Saturday's MLB game between the Marlins and Mets at loanDepot park is scheduled to start at 4:10PM ET.

• Who: New York Mets vs. Miami Marlins
• Date: Saturday, September 27, 2025
• Time: 4:10PM ET/1:10PM PT
• Venue: loanDepot park

Dimers' comprehensive preview of Saturday's Mets vs. Marlins matchup includes our prediction, picks and the latest betting odds.

Before making any Mets vs. Marlins picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Mets, with a 59% win probability, will likely beat the Marlins on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Mets vs. Marlins insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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