Mets vs. Reds prediction: Why Mets are favored to win Friday's MLB matchup [9/5/2025]

The Cincinnati Reds will face the New York Mets in MLB action at Great American Ball Park on Friday, beginning at 6:40PM ET.

Andrew Abbott (8-5, 2.66 ERA) will start for the Reds, pitting him against David Peterson (8-5, 3.61 ERA) for the Mets.

Based on the latest simulations, Dimers' advanced MLB model predicts the Mets as the most likely winner of today's game.

For expanded analysis of Friday's matchup, including best bets and picks, visit our interactive Mets vs. Reds predictions page.

Reds vs. Mets prediction: Who will win, cover the run line?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Friday's MLB game between the Mets and Reds 10,000 times as part of our MLB predictions coverage.

Our independent predictive model currently gives the Mets a 53% chance of defeating the Reds.

According to our model, the Reds (+1.5) have a 59% chance of covering the run line, while the 9.5-run over/under has a 53% chance of staying under.

Mets vs. Reds odds [9/5/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Mets	Reds
Run Line	-1.5 (+136)	+1.5 (-160)
Moneyline	-115	+100
Total	o9.5 (+100)	u9.5 (-119)

All odds are correct at the time of publication and are subject to change.

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Mets vs. Reds picks and best bets

Our model's biggest edge in today's Mets vs. Reds matchup is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets video

Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.

Mets vs. Reds game-day updates and essential details

Friday's MLB game between the Reds and Mets at Great American Ball Park is scheduled to commence at 6:40PM ET.

• Who: New York Mets vs. Cincinnati Reds
• Date: Friday, September 5, 2025
• Time: 6:40PM ET/3:40PM PT
• Venue: Great American Ball Park

Dimers.com's comprehensive preview of Friday's Mets vs. Reds matchup includes our prediction, picks and the latest betting odds.

Before making any Mets vs. Reds picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Mets, with a 53% win probability, will likely beat the Reds on Friday.

AI and automation have enhanced this article to quickly deliver accurate Mets vs. Reds insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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