Mets vs. Cubs prediction: Why Mets are favored to win Wednesday's MLB matchup [9/24/2025]

The Chicago Cubs will square off with the New York Mets, in what is expected to be a close MLB game, at Wrigley Field on Wednesday, commencing at 8:05PM ET.

The Cubs will send Matthew Boyd (13-8, 3.20 ERA) to the mound, while the Mets are going with Jonah Tong (2-2, 5.94 ERA).

Based on updated simulation results, Dimers' advanced MLB model predicts the Mets as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Mets-Cubs game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Mets' chance of winning at 51%, with the Cubs at 49%."

For further insights into Wednesday's matchup, including best bets and picks, visit our interactive Mets vs. Cubs predictions page.

Cubs vs. Mets prediction: Who will win?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Wednesday's MLB matchup between the Mets and Cubs 10,000 times as part of our MLB predictions coverage.

Our leading predictive model gives the Mets a 51% chance of beating the Cubs.

According to our model, the over/under total of 7.5 runs has a 58% chance of going over.

Mets vs. Cubs odds [9/24/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Mets	Cubs
Moneyline	+100	-118
Total	o7.5 (+114)	u7.5 (-130)

All odds are correct at the time of publication and are subject to change.

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Mets vs. Cubs picks and best bets

Our model's biggest edge in today's Mets vs. Cubs matchup is on the moneyline.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free ⚾️ picks

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Mets vs. Cubs game-day updates and essential details

Wednesday's MLB matchup between the Cubs and Mets at Wrigley Field is scheduled to start at 8:05PM ET.

• Who: New York Mets vs. Chicago Cubs
• Date: Wednesday, September 24, 2025
• Time: 8:05PM ET/5:05PM PT
• Venue: Wrigley Field

Dimers' full preview of Wednesday's Mets vs. Cubs matchup includes our prediction, picks and the latest betting odds.

Before making any Mets vs. Cubs picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Mets, with a 51% win probability, will likely beat the Cubs on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Mets vs. Cubs insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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