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Knicks vs. Cavaliers Prediction: Cleveland to Win, Jalen Brunson Projected for Big Game in Friday's NBA Matchup [2/21/2025]

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Written by Ryan Leaver

Our expert prediction for Friday's New York Knicks vs Cleveland Cavaliers matchup.

New York Knicks-Cleveland Cavaliers Predictions and Game Preview.
Rocket Arena sets the stage for the NBA matchup between the New York Knicks and Cleveland Cavaliers this Friday.

The Cleveland Cavaliers will square off with the New York Knicks in NBA action at Rocket Arena on Friday, commencing at 7:00PM ET.

Based on the latest simulation results and today’s injury reports, Dimers' advanced NBA model (see Dimers Pro for full access) projects the Cavaliers as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's New York-Cleveland game 10,000 times," said Damien Souness from Dimers.

"After computing the latest updates and thousands of other inputs, we predict the Cavaliers' chance of winning is 71%, while the Knicks' is 29%."

This prediction follows the latest NBA Injury Report, which suggests the Cavaliers lineup will feature players like Donovan Mitchell, Darius Garland and Evan Mobley, while the Knicks will be led by Jalen Brunson, Karl-Anthony Towns and Mikal Bridges.

For expanded analysis of Friday's matchup, including an expanded look at the predicted score, best bets and player prop picks, visit our interactive Knicks vs. Cavaliers predictions page.

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Cavaliers vs. Knicks Prediction: Who Will Win, Cover the Spread?

Using powerful machine learning and data, we have simulated the outcome of Friday's NBA game between the Knicks and Cavaliers 10,000 times as part of our NBA predictions coverage.

Our leading predictive model gives the Cavaliers a 71% chance of beating the Knicks. Our predicted final score has the Cavaliers winning 123-116.

According to our model, the Knicks (+7.5) have a 53% chance of covering the spread, while the over/under total of 241.5 points has a 54% chance of staying under.

 

Knicks vs. Cavaliers Odds

We have sourced the best NBA odds in America for this game, which are listed here:

Bet Type Knicks Cavaliers
Spread +7.5 (-108) -7.5 (-105)
Moneyline +240 -290
Total o241.5 (-110) u241.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Knicks vs. Cavaliers Picks and Best Bets

Our model's biggest edge in today's Knicks vs. Cavaliers matchup is on the spread.

Our expert predictions, matched against the current odds, reveal the best NBA picks for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Knicks vs. Cavaliers Player Props

NBA player props are a common way to wager on the Knicks vs. Cavaliers matchup without necessarily betting on the outcome. We have crunched the numbers to project how each team's leading players will perform at Rocket Arena.

Jalen Brunson is expected to lead the Knicks in scoring, while Donovan Mitchell is projected to be the top scorer for the Cavaliers.

Jalen Brunson 2025.
Jalen Brunson is projected to be one of the top scorers in tonight's game.

Dimers Pro users can access a full range of player props and projected box scores, including points, assists, rebounds and more, for every NBA game this season.

Calling Our Shot's Free 🏀 Picks

Calling Our Shot produces daily NBA betting content, including the free picks featured below.

Knicks vs. Cavs Game-Day Updates and Essential Details

Friday's game between the Cavaliers and Knicks at Rocket Arena is scheduled to begin at 7:00PM ET.

Dimers.com's in-depth preview of Friday's Knicks vs. Cavaliers matchup includes our prediction, picks and the latest betting odds.

Before making any New York vs. Cleveland picks, be sure to check out the latest NBA predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Cavaliers, with a 71% win probability, will likely beat the Knicks on Friday.

AI and automation have enhanced this article to quickly deliver accurate Knicks vs. Cavaliers insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on NBA

Keep up with the latest NBA betting news, NBA best bets and NBA parlay picks throughout the season. Plus, our NBA championship odds provide the most up-to-date probabilities for the NBA title.

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Written by
Ryan Leaver
Senior Sports and Betting Editor

Ryan Leaver uses advanced statistical models and simulations to predict outcomes and provide predictions for the NBA, NFL, college football, college basketball, and soccer. He offers detailed game previews, best bets, props, and futures articles.

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