Saints vs. Seahawks prediction: Seattle favored to win in NFL Week 3, 2025

The Seattle Seahawks and New Orleans Saints are scheduled to meet in Week 3 of the NFL season at Lumen Field on Sunday, with kickoff at 4:05PM ET.

Based on updated simulations, Dimers' proven NFL model projects the Seahawks as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Saints-Seahawks game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Seahawks with a win probability of 76%, while the Saints have 24%."

This gameday Saints vs. Seahawks betting preview builds on my Saints vs. Seahawks prediction that was posted earlier in the week.

For expanded analysis of today’s game, including the predicted score, best bets and player prop picks, visit our interactive Saints vs. Seahawks predictions page.

Saints vs. Seahawks Predictions

Since our Saints-Seahawks predictions earlier in the week, we have simulated the outcome of Sunday's NFL matchup between the Saints and Seahawks 10,000 times as part of our NFL predictions coverage.

Our independent predictive model gives the Seahawks a 76% chance of defeating the Saints in Week 3 of the NFL season. Our predicted final score has the Seahawks winning 24-17.

According to our model, the Saints (+7) have a 54% chance of covering the spread, while the 41.5-point over/under has an equal 50-50 chance of hitting.

Saints vs. Seahawks odds

We have researched the best NFL odds in America for this game, which are listed here:

Bet Type	Saints	Seahawks
Spread	+7 (-105)	-7 (-115)
Moneyline	+315	-375
Total	o41.5 (-112)	u41.5 (-108)

All odds are correct at the time of publication and are subject to change.

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Saints vs. Seahawks picks and best bets

Our model's biggest edge in today's Saints vs. Seahawks matchup is on the over/under.

Our expert predictions, aligned with the latest odds, reveal the best NFL picks and NFL best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Saints vs. Seahawks TD scorers

Who will score the first touchdown in Saints vs. Seahawks?

According to our model, Seattle's Kenneth Walker is most likely to score the first touchdown in Saints vs. Seahawks.

Our projections give Walker a 17.0% chance of scoring the first TD at Lumen Field, while the Seahawks running back is a 57.5% chance of reaching the end zone at any point in the game.

First touchdown scorer predictions

New Orleans Saints

Player	First TD Probability
Alvin Kamara (RB)	11.0%
Juwan Johnson (TE)	5.7%
Chris Olave (WR)	5.6%

Seattle Seahawks

Player	First TD Probability
Kenneth Walker (RB)	17.0%
Jaxon Smith-Njigba (WR)	9.4%
Cooper Kupp (WR)	6.9%

Anytime touchdown scorer predictions

New Orleans Saints

Player	Anytime TD Probability
Alvin Kamara (RB)	40.3%
Juwan Johnson (TE)	23.4%
Chris Olave (WR)	23.0%

Seattle Seahawks

Player	Anytime TD Probability
Kenneth Walker (RB)	57.5%
Jaxon Smith-Njigba (WR)	37.6%
Cooper Kupp (WR)	29.3%

Saints vs Seahawks player props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Saints and Seahawks. For detailed projections, join Dimers Pro.

Already a Dimers Pro member? Head to our Saints-Seahawks page now to access every player prop projection.

Saints vs. Seahawks quarterbacks

Of the starting quarterbacks, the Saints' Spencer Rattler is projected to throw for fewer yards than the Seahawks' Sam Darnold.

Saints rushing

Alvin Kamara, Spencer Rattler and Kendre Miller are projected to be the leading rushers for the Saints.

Player	Position
Alvin Kamara	RB
Spencer Rattler	QB
Kendre Miller	RB

Seahawks rushing

Kenneth Walker, George Holani and Sam Darnold are expected to lead the Seahawks in rushing yards.

Player	Position
Kenneth Walker	RB
George Holani	RB
Sam Darnold	QB

Saints receiving

Chris Olave, Juwan Johnson, Rashid Shaheed, Alvin Kamara and Brandin Cooks are projected to top the receiving yards for the Saints.

Player	Position
Chris Olave	WR
Juwan Johnson	TE
Rashid Shaheed	WR
Alvin Kamara	RB
Brandin Cooks	WR

Seahawks receiving

Jaxon Smith-Njigba, Cooper Kupp, Tory Horton, AJ Barner and Kenneth Walker are projected to lead the Seahawks in receiving yards.

Player	Position
Jaxon Smith-Njigba	WR
Cooper Kupp	WR
Tory Horton	WR
AJ Barner	TE
Kenneth Walker	RB

Saints vs. Seahawks game-day updates and essential details

The NFL Week 3 game between the Seahawks and Saints at Lumen Field is scheduled to commence at 4:05PM ET.

• Who: New Orleans Saints vs. Seattle Seahawks
• Date: Sunday, September 21, 2025
• Time: 4:05PM ET/1:05PM PT
• Venue: Lumen Field

Dimers' comprehensive preview of this week's Saints vs. Seahawks matchup includes our prediction, picks and the latest betting odds.

Before making any Saints vs. Seahawks picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Seahawks, with a 76% win probability, will likely beat the Saints in Week 3 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate Saints vs. Seahawks insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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