New England Patriots vs. Miami Dolphins early prediction: Expert picks for NFL Week 2, 2025

The New England Patriots and Miami Dolphins will meet in Week 2 of the NFL season at Hard Rock Stadium on Sunday, September 14, 2025, starting at 1:00PM ET.

Initial simulations from Dimers' trusted NFL model favor the Dolphins as the most likely winner of this matchup.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Patriots vs. Dolphins predictions page.

New England vs. Miami early predictions

Leveraging trusted machine learning and analysis, we have simulated the Patriots vs. Dolphins game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Patriots 42%, Dolphins 58%
• Predicted final score: Patriots 21-23 Dolphins
• Spread: Patriots (+2.5) 50%, Dolphins (-2.5) 50%
• Total points (45.5): Over 50%, Under 50%

As of September 7, 2025, these Patriots-Dolphins numbers and predictions reflect the latest data and insights available.

Patriots vs. Dolphins Week 2 details

The NFL Week 2 action between the Dolphins and Patriots at Hard Rock Stadium is scheduled for September 14, 2025.

• Who: New England Patriots vs. Miami Dolphins
• Date: Sunday, September 14, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: Hard Rock Stadium

Patriots vs. Dolphins opening odds

We've researched the best betting odds across America for this Week 2 game, which are listed here:

• Spread: Patriots +2.5 (-110), Dolphins -2.5 (-110)
• Moneyline: Patriots +114, Dolphins -135
• Total: Over/Under 45.5 (-110/-110)

Odds may continue to move—track live changes via our NFL odds page.

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Conclusion

We predict the Dolphins, with a 58% win probability, will likely beat the Patriots in Week 2 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Patriots vs. Dolphins matchup, with human oversight maintaining high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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