Naomi Osaka vs. Amanda Anisimova prediction, odds, picks for US Open 2025

Naomi Osaka will face Amanda Anisimova in the semifinals of the US Open Women's Singles 2025 on Thursday.

Based on the latest simulation results, Dimers' advanced tennis model predicts Naomi Osaka as the most likely winner of the match.

For further insights into Thursday's match, including best bets and picks, visit our interactive Osaka vs. Anisimova predictions page.

Osaka vs. Anisimova prediction: Who will win and advance to the final?

Using trusted machine learning and data analysis, we have simulated the result of Thursday's Osaka-Anisimova women's singles match 10,000 times as part of our tennis predictions coverage.

Our famous predictive model gives Osaka a 51% chance of winning against Anisimova in the US Open 2025.

Additionally, Osaka has a 51% chance of winning the first set, while the under 22.5 games has a 53% chance of hitting, according to our model.

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Naomi Osaka vs. Amanda Anisimova odds

We have researched the most up-to-date betting odds in America for this match, which are listed here:

Bet Type	Osaka	Anisimova
Moneyline	-111	+100
First Set	-111	-111
Total Games	o22.5 (-105)	u22.5 (-120)

All odds are correct at the time of publication and are subject to change.

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Osaka vs. Anisimova picks and best bets

Our model's biggest edge in today's Osaka vs. Anisimova match is on the moneyline.

Our expert predictions, aligned with the latest odds, reveal the best tennis picks and tennis best bets for every tournament throughout the year.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Osaka vs. Anisimova updates and essential details

The US Open 2025 match between Naomi Osaka and Amanda Anisimova is scheduled to start on Thursday at 9:50PM ET.

• Who: Naomi Osaka vs. Amanda Anisimova
• Date: Thursday, September 4, 2025
• Approx. Time: 9:50PM ET/6:50PM PT
• Tournament: US Open Women's Singles 2025
• Round: Semifinals

All dates and times mentioned in this article are United States Eastern Time unless otherwise noted.

Dimers.com's full preview of Thursday's Osaka vs. Anisimova match includes our prediction, picks and the latest betting odds.

Before making any Naomi Osaka vs. Amanda Anisimova picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.

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Conclusion

We predict Naomi Osaka, with a 51% win probability, will likely beat Amanda Anisimova at the US Open 2025.

AI and automation have enhanced this article to quickly deliver accurate Osaka vs. Anisimova insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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