MLB player props today: Top Monday plays include Sal Frelick [9/22/2025]

Our MLB player props for Monday, September 22, 2025, are locked and loaded, chosen through cutting-edge simulations and machine learning techniques.

These MLB player props are designed to enhance your betting strategy and feature players like Sal Frelick, Xander Bogaerts and Freddy Peralta.

Three of today's prop betting opportunities are listed below, with Dimers Pro users receiving unlimited access to our full suite of prop picks and today's MLB pitcher projections.

Join Dimers Pro now to unlock our complete set of data-driven props and best bets.

List of MLB prop picks for Monday

While the MLB prop picks on this page for Monday are sorted by win probability, betting on likelihood alone means leaving money on the table.

Savvy bettors chase edge—not just probability—and the highest-edge picks are reserved for Dimers Pro users to give them the best shot at winning.

Sal Frelick to get a hit (-157)

• Probability: 64.7%
• Edge: 3.6%
• Game: Brewers vs. Padres (9:40PM ET)

Our model has found a standout MLB prop for Monday's Brewers vs. Padres matchup, zeroing in on Milwaukee's Sal Frelick. With a 64.7% chance of hitting, we suggest betting on Sal Frelick to get a hit at -157 odds, offering an edge of 3.6%.

Xander Bogaerts to get a hit (-155)

• Probability: 63.6%
• Edge: 2.8%
• Game: Brewers vs. Padres (9:40PM ET)

Our model has identified another high-probability prop for Monday's MLB action, with San Diego's Xander Bogaerts in our sights in the Brewers-Padres game. We recommend betting on Xander Bogaerts to get a hit with an edge of 2.8% at -155 odds.

Freddy Peralta over 1.5 earned runs (-125)

• Probability: 63.2%
• Edge: 7.6%
• Game: Brewers vs. Padres (9:40PM ET)

According to our analysis, another strong prop for today's MLB action focuses on Milwaukee's Freddy Peralta in the Brewers vs. Padres game. The recommended bet is Freddy Peralta over 1.5 earned runs at -125 odds, with a 63.2% chance of hitting and a 7.6% edge.

MLB player prop picks: Monday, September 22, 2025

A quick summary of today’s top three props by probability according to our model as of 8:51PM ET:

Matchup	Prop	Odds	Probability	Edge
Brewers vs. Padres	Sal Frelick To Get a Hit	-157 @ DraftKings	64.7%	3.6%
Brewers vs. Padres	Xander Bogaerts To Get a Hit	-155 @ BetMGM	63.6%	2.8%
Brewers vs. Padres	Freddy Peralta Over 1.5 Earned Runs	-125 @ BetMGM	63.2%	7.6%

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Monday's MLB slate features a total of 70 MLB player props at the time of writing, all backed by real betting value.

More about MLB

The prop bets on this page are part of our MLB player props and MLB best bets series.

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Conclusion

For September 22, 2025, our MLB prop bets are locked and loaded, featuring players like Sal Frelick, Xander Bogaerts and Freddy Peralta. Powered by cutting-edge simulations, these picks are here to give your betting strategy the edge it needs.

With the help of AI and automation, this article delivers today's MLB prop bets and insights quickly and accurately, while human oversight ensures high editorial quality. Our predictions are based on current data to help you make informed decisions.

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