MLB Player Props Today: Wednesday's Top Plays Include Kyle Isbel [8/6/2025]

Our MLB player props for Wednesday, August 6, 2025, are locked and loaded, generated through groundbreaking simulations and machine learning techniques.

These MLB player props are here today to enhance your betting strategy and feature players like Kyle Isbel, George Kirby and Spencer Strider.

Three of today's prop betting opportunities are listed below, with Dimers Pro subscribers getting unlimited access to our full suite of prop picks and Wednesday's MLB pitcher projections.

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List of MLB Prop Bets for Wednesday

While the MLB prop picks on this page for Wednesday are sorted by win probability, betting on likelihood alone means leaving money on the table.

Smart bettors chase edge—not just probability—and the highest-edge picks are reserved for Dimers Pro users to give them the best shot at winning.

Kyle Isbel To Get a Hit (-140)

• Probability: 62.3%
• Edge: 4.0%
• Game: Royals vs. Red Sox (7:10PM ET)

Our model has flagged a standout MLB prop for Wednesday's Royals vs. Red Sox game, focusing on Kansas City's Kyle Isbel. With a 62.3% chance of hitting, we suggest betting on Kyle Isbel To Get a Hit at -140 odds, offering an edge of 4.0%.

George Kirby Over 1.5 Earned Runs (-140)

• Probability: 62.2%
• Edge: 3.9%
• Game: White Sox vs. Mariners (9:40PM ET)

Our model has identified another high-probability prop for today's MLB action, with Seattle's George Kirby in our sights in the White Sox-Mariners game. We suggest betting on George Kirby Over 1.5 Earned Runs at -140 odds, backed by a 62.2% chance of hitting and a 3.9% edge.

Spencer Strider Over 1.5 Earned Runs (-145)

• Probability: 61.9%
• Edge: 2.7%
• Game: Brewers vs. Braves (7:15PM ET)

According to our analysis, another strong prop for Wednesday's MLB action focuses on Atlanta's Spencer Strider in the Brewers vs. Braves game. The recommended bet is Spencer Strider Over 1.5 Earned Runs at -145 odds, with a 61.9% chance of hitting and a 2.7% edge.

MLB Player Prop Picks: Wednesday, August 6, 2025

A quick summary of today’s top three props by probability according to our model as of 5:56PM ET:

Matchup	Prop	Odds	Probability	Edge
Royals vs. Red Sox	Kyle Isbel To Get a Hit	-140 @ DraftKings	62.3%	4.0%
White Sox vs. Mariners	George Kirby Over 1.5 Earned Runs	-140 @ DraftKings	62.2%	3.9%
Brewers vs. Braves	Spencer Strider Over 1.5 Earned Runs	-145 @ DraftKings	61.9%	2.7%

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Wednesday's MLB slate features a total of 245 MLB player props at the time of writing, all backed by real betting value.

More About MLB

The prop bets on this page are part of our MLB player props and MLB best bets series.

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Conclusion

For August 6, 2025, our MLB prop bets are locked and loaded, featuring players like Kyle Isbel, George Kirby and Spencer Strider. Backed by the latest data and advanced simulations, these picks are here to make sure you're betting smarter, not harder.

With the help of AI and automation, this article delivers today's MLB prop bets and insights quickly and accurately, while human oversight ensures high editorial quality. Our predictions are rooted in the latest data to help you make informed decisions.

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