MLB player props today: Top Friday plays include Michael Harris II [9/12/2025]

Our MLB player props for Friday, September 12, 2025, are locked and loaded, generated through cutting-edge simulations and advanced machine learning.

These MLB player props are here today to enhance your betting strategy and feature players such as Michael Harris II, Otto Lopez and Mauricio Dubon.

Three of today's prop betting opportunities are listed below, with Dimers Pro members getting unlimited access to our full suite of prop picks and today's MLB hitter projections.

Today's full list of MLB prop bets is led by a player in the Orioles vs. Blue Jays game to go under his outs recorded line, with our in-house predictive model identifying an edge of 12% at +130 odds.

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List of MLB prop picks for Friday

While the MLB prop picks on this page for Friday are sorted by win probability, betting on likelihood alone means leaving money on the table.

Savvy bettors chase edge—not just probability—and the highest-edge picks are reserved for Dimers Pro users to give them the best chance at winning.

Michael Harris II to get a hit (-183)

• Probability: 68.0%
• Edge: 3.3%
• Game: Astros vs. Braves (7:15PM ET)

Our model has flagged a strong MLB prop for Friday's Astros vs. Braves game, focusing on Atlanta's Michael Harris II. With a 68.0% chance of hitting, we suggest betting on Michael Harris II to get a hit at -183 odds, offering an edge of 3.3%.

Otto Lopez to get a hit (-190)

• Probability: 67.6%
• Edge: 2.1%
• Game: Tigers vs. Marlins (7:10PM ET)

Our model has identified another high-probability prop for today's MLB action, with Miami's Otto Lopez in our sights in the Tigers-Marlins game. We suggest betting on Otto Lopez to get a hit with an edge of 2.1% at -190 odds.

Mauricio Dubon to get a hit (-171)

• Probability: 66.9%
• Edge: 3.8%
• Game: Astros vs. Braves (7:15PM ET)

According to our analysis, another strong prop for today's MLB action focuses on Houston's Mauricio Dubon in the Astros vs. Braves game. The recommended bet is Mauricio Dubon to get a hit at -171 odds, with a 66.9% chance of hitting and a 3.8% edge.

MLB player prop picks: Friday, September 12, 2025

A quick summary of today’s top three props by probability according to our model as of 5:57PM ET:

Matchup	Prop	Odds	Probability	Edge
Astros vs. Braves	Michael Harris II To Get a Hit	-183 @ DraftKings	68.0%	3.3%
Tigers vs. Marlins	Otto Lopez To Get a Hit	-190 @ BetMGM	67.6%	2.1%
Astros vs. Braves	Mauricio Dubon To Get a Hit	-171 @ DraftKings	66.9%	3.8%

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Friday's MLB props include a standout play with an edge of 12% on the best available odds—the kind of high-value bet you won't find by chasing probability alone.

Dimers Pro users have access to 288 MLB player props at the time of writing, all backed by real betting value.

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More about MLB

The prop bets on this page are part of our MLB player props and MLB best bets series.

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Conclusion

For September 12, 2025, our MLB prop bets are locked and loaded, featuring players like Michael Harris II, Otto Lopez and Mauricio Dubon. Backed by the latest data and advanced simulations, these picks are here to make sure you're betting smarter, not harder.

With the help of AI and automation, this article delivers today's MLB prop bets and insights quickly and accurately, while human oversight ensures high editorial quality. Our predictions are grounded in the latest data to help you make informed decisions.

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