Home run predictions for Sunday include Aaron Judge, Giancarlo Stanton [9/21/2025]

Our MLB home run predictions for Sunday, September 21, 2025, are in—with Aaron Judge topping the list based on the latest Dimers Pro simulation data.

Sunday's HR projections pull from our full list of home run predictions, built to highlight the most likely home run hitters today.

Home run predictions for September 21, 2025

Our analysis shows Judge leads today's MLB home run predictions with a 25.1% chance to go yard, followed by Kyle Schwarber (23.5%) and Giancarlo Stanton (22.7%).

Cal Raleigh and Jo Adell are among several other sluggers to crack the top 10. Want the full list of home run props today—including every player's HR prediction for Sunday? Join Dimers Pro now.

Already a Dimers Pro member? Check out today's HR and hitter projections and sort by “To Hit HR” to see every player’s probability of going deep.

Sunday's home run picks [9/21/2025]

After running 10,000 simulations per matchup and assessing key variables like weather and pitching matchups, Dimers Pro has identified one of the best MLB home run props today.

Jac Caglianone (Royals) to hit a home run

• Probability: 15.1%
• Odds: +825
• Edge: 4.3%
• Game: Blue Jays vs. Royals (2:10PM ET)
• Pitching matchup: Trey Yesavage

Despite not cracking the top 10 in today's home run predictions, Kansas City slugger Jac Caglianone offers standout value at +825 with BetMGM, showing an edge of 4.3%—making him one of the strongest home run bets today.

Set to face Trey Yesavage in tonight's Blue Jays-Royals matchup, factoring in both projection edge and odds, Caglianone has emerged as the one of the best home run picks today on Sunday's slate.

For more expert MLB picks and data-led MLB predictions, join Dimers Pro now. Pro users get full access to a total of 99 home run predictions today, plus hit and RBI projections, pitcher props, and more—perfect for building smarter MLB parlays and round robins.

MLB schedule for today [Sunday, September 21, 2025]

• Yankees vs. Orioles (1:35PM ET, Sunday)
• Athletics vs. Pirates (1:35PM ET, Sunday)
• Braves vs. Tigers (1:40PM ET, Sunday)
• Nationals vs. Mets (1:40PM ET, Sunday)
• Blue Jays vs. Royals (2:10PM ET, Sunday)
• Guardians vs. Twins (2:10PM ET, Sunday)
• Padres vs. White Sox (2:10PM ET, Sunday)
• Brewers vs. Cardinals (2:15PM ET, Sunday)
• Angels vs. Rockies (3:10PM ET, Sunday)
• Phillies vs. D-Backs (4:10PM ET, Sunday)
• Mariners vs. Astros (7:10PM ET, Sunday)
• Red Sox vs. Rays (7:35PM ET, Sunday)

Bet365 bonus code "DIMERS" — perfect for home run betting

To make the most of our dinger picks, headlined by the strong betting edge on Jac Caglianone, check out the latest Bet365 bonus code of "DIMERS" that scores you $200 in bonus bets from a $5 bet – win or lose.

This Referral Code is used for marketing/tracking purposes only. Minimum $10 deposit required. Minimum odds -500 of greater. Bonus Bets wager excluded from returns. New customers only. T&CS, time limits and exclusions apply..

Conclusion

For September 21, 2025, our MLB home run predictions are locked in, with sluggers like Aaron Judge, Kyle Schwarber and Giancarlo Stanton projected to be among the most powerful bats in today’s games. But it's Jac Caglianone who stands out as the best value bet, offering an appealing 4.3% edge at +825 odds.

These insights are based on 10,000 game simulations and are designed to help you identify smarter betting opportunities. As always, gamble responsibly. If you or someone you know needs support, call 1-800-GAMBLER.

For more coverage, check out today's MLB player props and MLB best bets. Plus, stay updated with the latest MLB news, MLB betting trends updated every 15 minutes, and World Series odds.

Note: This article may include affiliate links. Learn how we review products and services.