Home run predictions for Wednesday include Aaron Judge, Kyle Schwarber [9/10/2025]

Our MLB home run predictions for Wednesday, September 10, 2025, are in—with Aaron Judge leading the list based on the latest Dimers Pro simulation data.

Wednesday's HR projections come straight from our home run predictions, which simulate every MLB matchup 10,000 times to reveal the top slugging candidates today.

Home run predictions for September 10, 2025

Our analysis shows Judge leads today's MLB home run predictions with a 24.5% chance to go yard, followed by Kyle Schwarber (23.3%) and Giancarlo Stanton (22.7%).

Shohei Ohtani and Cal Raleigh are among several other sluggers to crack the top 10. Want the full list of home run props today—including every player's HR prediction for Wednesday? Join Dimers Pro now.

Already a Dimers Pro member? Check out today's HR and hitter projections and sort by “To Hit HR” to see every player’s probability of going deep.

Wednesday's home run picks [9/10/2025]

After running 10,000 simulations per matchup and evaluating key factors like weather and pitching matchups, Dimers Pro has identified one of the best MLB home run props today.

Coby Mayo (Orioles) to hit a home run

• Probability: 12.5%
• Odds: +1200
• Edge: 4.8%
• Game: Pirates vs. Orioles (6:35PM ET)
• Pitching matchup: Paul Skenes

Despite not cracking the top 10 in today's home run predictions, Baltimore slugger Coby Mayo offers standout value at +1200 with BetMGM, showing an edge of 4.8%—making him one of the strongest home run bets today.

Set to face Paul Skenes in tonight's Pirates-Orioles matchup, factoring in both projection edge and odds, Mayo has emerged as the one of the best home run picks today on Wednesday's slate.

For more expert MLB picks and data-driven MLB predictions, join Dimers Pro now. Pro users get full access to a total of 71 home run predictions today, plus hit and RBI projections, pitcher props, and more—perfect for building smarter MLB parlays and round robins.

MLB schedule for today [Wednesday, September 10, 2025]

• Brewers vs. Rangers (2:35PM ET, Wednesday)
• Red Sox vs. Athletics (3:35PM ET, Wednesday)
• D-Backs vs. Giants (3:45PM ET, Wednesday)
• Twins vs. Angels (4:07PM ET, Wednesday)
• Pirates vs. Orioles (6:35PM ET, Wednesday)
• Royals vs. Guardians (6:40PM ET, Wednesday)
• Nationals vs. Marlins (6:40PM ET, Wednesday)
• Mets vs. Phillies (6:45PM ET, Wednesday)
• Tigers vs. Yankees (7:05PM ET, Wednesday)
• Astros vs. Blue Jays (7:07PM ET, Wednesday)
• Cubs vs. Braves (7:15PM ET, Wednesday)
• Reds vs. Padres (8:40PM ET, Wednesday)
• Cardinals vs. Mariners (9:40PM ET, Wednesday)

Conclusion

For September 10, 2025, our MLB home run predictions are locked in, with sluggers like Aaron Judge, Kyle Schwarber and Giancarlo Stanton projected to be among the most powerful bats in today’s games. But it's Coby Mayo who stands out as the best value bet, offering an appealing 4.8% edge at +1200 odds.

These insights are based on 10,000 game simulations and are designed to help you identify smarter betting opportunities. As always, gamble responsibly. If you or someone you know needs support, call 1-800-GAMBLER.

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