Free MLB picks today: Tuesday's MLB best bets revealed after 10,000 simulations [9/16/2025]

Today’s free MLB picks for September 16, 2025 are here, with Tuesday’s MLB best bets fueled by thousands of predictive simulations analyzing the latest odds and matchups.

Today's MLB best bets will be sourced from matchups such as Phillies vs. Dodgers, with this article updated throughout the day to feature the highest-probability plays based on thousands of data-driven simulations from our predictive analytics model.

Pro members get unlimited access to everything Dimers has to offer, including our complete set of picks and best bets for today and the week ahead.

List of MLB best bets today [9/16, updated 9:31PM ET]

After simulating today's remaining MLB games thousands of times, our model has determined there are no MLB bets worth making right now. This is because there are currently no valuable edges between our data-driven probabilities and the best available odds.

List of upcoming MLB games to bet on [9/16/2025]

• Giants vs. D-Backs (9:40PM ET, Tuesday)
• Phillies vs. Dodgers (10:10PM ET, Tuesday)
• Cubs vs. Pirates (12:35PM ET, Wednesday)
• Reds vs. Cardinals (1:15PM ET, Wednesday)
• Orioles vs. White Sox (2:10PM ET, Wednesday)
• Giants vs. D-Backs (3:40PM ET, Wednesday)
• Braves vs. Nationals (4:05PM ET, Wednesday)
• Guardians vs. Tigers (6:40PM ET, Wednesday)
• Athletics vs. Red Sox (6:45PM ET, Wednesday)
• Blue Jays vs. Rays (7:05PM ET, Wednesday)
• Padres vs. Mets (7:10PM ET, Wednesday)
• Yankees vs. Twins (7:40PM ET, Wednesday)
• Angels vs. Brewers (7:40PM ET, Wednesday)
• Mariners vs. Royals (7:40PM ET, Wednesday)
• Rangers vs. Astros (8:10PM ET, Wednesday)
• Marlins vs. Rockies (8:40PM ET, Wednesday)

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More on MLB

The bets on this page form part of our MLB player props and MLB best bets series.

For more MLB betting content, we have MLB trends for every game, as well as daily MLB betting news and the latest World Series odds and predictions.

Conclusion

Our MLB best bets are locked and loaded for September 16, 2025, with our in-house predictive analytics model constantly searching for bets across Tuesday's action.. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate MLB insights quickly, with human oversight ensuring high editorial quality. Our predictions are grounded in current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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