Free MLB picks today: Wednesday's MLB best bets include three over/under plays [9/24/2025]

Today’s free MLB picks for September 24, 2025 are here, with Wednesday’s MLB best bets fueled by thousands of predictive simulations analyzing the latest odds and matchups.

These MLB best bets include matchups like Rockies vs. Mariners and Dodgers vs. Diamondbacks, with this article updated throughout the day to feature the highest-probability plays based on thousands of data-driven simulations from our predictive analytics model.

But if you're serious about long-term profit, it's not just about probability—it's about edge. To unlock our highest-edge MLB bets—the ones with true long-term value—join Dimers Pro.

Pro members get unlimited access to everything Dimers has to offer on Wednesday, September 24, 2025, including our full suite of picks and best bets for today and the week ahead.

List of MLB best bets tonight [9/24, updated 9:32PM ET]

After diving deep into the numbers and running thousands of simulations, our independent predictive analytics model has figured out the best baseball bets for Wednesday, September 24, 2025.

Rockies vs. Mariners over 7.5 runs (-102)

• Probability: 58.5%
• Edge: 8.0%
• Matchup: Rockies vs. Mariners (9:40PM ET, Wednesday)

Our model has pinpointed a high-probability MLB betting opportunity tonight, which comes in the Rockies vs. Mariners matchup. We recommend an over/under bet on over 7.5 runs at -102 odds, with our analysis showing a 58.5% chance of hitting and a compelling edge of 8.0%.

Dodgers vs. Diamondbacks over 8.5 runs (-108)

• Probability: 58%
• Edge: 6.1%
• Matchup: Dodgers vs. Diamondbacks (9:40PM ET, Wednesday)

Our model has found another strong MLB bet for Wednesday's baseball action, this time in the matchup between the Dodgers and Diamondbacks. We suggest placing an over/under wager on over 8.5 runs at -108 odds, with a 58% probability delivering a 6.1% edge.

Cardinals vs. Giants over 7.5 runs (-115)

• Probability: 56.5%
• Edge: 3.0%
• Matchup: Cardinals vs. Giants (9:45PM ET, Wednesday)

Our model has found another strong MLB bet for tonight's baseball action, this time in the Cardinals vs. Giants game. We recommend an over/under bet on over 7.5 runs at -115 odds. Our projections shows a 56.5% probability and 3.0% edge for this wager.

MLB best bets: Wednesday, 9/24/2025

As of 9:32PM ET, here are our top three MLB bets by probability recommended by our model:

Matchup	Bet	Odds	Probability	Edge
Rockies vs. Mariners	Over 7.5 Runs	-102 @ BetMGM	58.5%	8.0%
Dodgers vs. Diamondbacks	Over 8.5 Runs	-108 @ DraftKings	58%	6.1%
Cardinals vs. Giants	Over 7.5 Runs	-115 @ FanDuel	56.5%	3.0%

Dimers Pro unlocks instant access to the most valuable bets across all sports, powered by our advanced predictive model.

Today, Dimers Pro subscribers have access to 12 MLB picks—with access to all of these being what makes a difference over time.

Join Dimers Pro now to access these picks, as well as a comprehensive range of props, trends and parlays for September 24, 2025.

List of upcoming MLB games to bet on [9/24/2025]

• Royals vs. Angels (9:38PM ET, Wednesday)
• Dodgers vs. D-Backs (9:40PM ET, Wednesday)
• Rockies vs. Mariners (9:40PM ET, Wednesday)
• Cardinals vs. Giants (9:45PM ET, Wednesday)
• Astros vs. Athletics (10:05PM ET, Wednesday)
• Pirates vs. Reds (12:40PM ET, Thursday)
• Rays vs. Orioles (1:05PM ET, Thursday)
• Dodgers vs. D-Backs (3:40PM ET, Thursday)
• Marlins vs. Phillies (6:05PM ET, Thursday)
• White Sox vs. Yankees (7:05PM ET, Thursday)
• Red Sox vs. Blue Jays (7:07PM ET, Thursday)
• Mets vs. Cubs (7:40PM ET, Thursday)

More about MLB

The bets on this page form part of our MLB player props and MLB best bets series.

For more MLB betting content, we have MLB trends for every game, as well as daily MLB betting news and the latest World Series odds and predictions.

Conclusion

Our MLB best bets are locked and loaded for September 24, 2025, featuring plays such as over 7.5 runs in the Rockies vs. Mariners matchup and over 8.5 runs in the Dodgers vs. Diamondbacks matchup. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate MLB insights quickly, with human oversight ensuring high editorial quality. Our predictions are drawn from current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

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