MLB picks today: Tuesday's MLB best bets include two over/under plays [9/23/2025]

Today's MLB picks for September 23, 2025 are here, with Tuesday’s MLB best bets built on thousands of predictive simulations analyzing the latest odds and matchups.

These MLB best bets include matchups like Brewers vs. Padres and Rockies vs. Mariners, with this article updated throughout the day to feature the highest-probability plays based on thousands of data-driven simulations from our predictive analytics model.

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Pro members get unlimited access to everything Dimers has to offer on Tuesday, September 23, 2025, including our full set of picks and best bets for today and the week ahead.

List of MLB best bets tonight [9/23, updated 9:33PM ET]

After digging deep into the numbers and conducting thousands of simulations, our famous predictive analytics model has figured out the best baseball bets for Tuesday, September 23, 2025.