Free MLB Picks Today: Friday's MLB Best Bets Include Orioles vs. Athletics Play [6/6/2025]

Another action-packed MLB slate is on deck for 6/6, and we've locked in our free MLB picks for today and MLB best bets today to help you cash in on Friday's action.

Today's MLB best bets include matchups like the Orioles vs. Athletics game at 10:05PM ET, with this article updated throughout the day to feature the highest-probability plays based on thousands of data-driven simulations from our predictive analytics model.

But if you're serious about long-term profit, it's not just about probability—it's about edge. To unlock our highest-edge MLB bets—the ones with true long-term value—join Dimers Pro.

Pro members get unlimited access to everything Dimers has to offer on Friday, June 6, 2025, including our full suite of MLB picks and best bets.

List of MLB Best Bets Tonight [6/6, Updated 10:01PM ET]

After crunching the numbers and running thousands of simulations, our famous predictive analytics model has identified the best baseball bet for Friday, June 6, 2025.

This is the only free pick available right now. Our full set of MLB predictions is exclusive to Dimers Pro.

Orioles vs. Athletics Under 10.5 Runs (-110)

• Probability: 56.7%
• Edge: 4.3%
• Matchup: Orioles vs. Athletics (10:05PM ET, Friday)

Our model has pinpointed a high-probability MLB betting opportunity tonight, which comes in the Orioles vs. Athletics matchup. We recommend an over/under bet on Under 10.5 Runs at -110 odds, with our analysis showing a 56.7% chance of hitting and a compelling edge of 4.3%.

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The bets listed here are sorted by win probability—but the real path to profit lies in high-edge plays. Dimers Pro unlocks instant access to the most valuable bets across all sports, powered by our advanced predictive model.

Among today's MLB picks is a +155 run line bet with a 6.1% edge—the kind of high-upside play that makes a difference over time.

Join Dimers Pro now to access these picks, as well as a comprehensive range of props, trends and parlays for June 6, 2025.

List of Upcoming MLB Games to Bet On [6/6/2025]

• Orioles vs. Athletics (10:05PM ET, Friday)
• Braves vs. Giants (10:15PM ET, Friday)
• Cubs vs. Tigers (1:10PM ET, Saturday)
• Blue Jays vs. Twins (2:10PM ET, Saturday)
• Dodgers vs. Cardinals (2:15PM ET, Saturday)
• Rangers vs. Nationals (4:05PM ET, Saturday)
• Phillies vs. Pirates (4:05PM ET, Saturday)
• Braves vs. Giants (4:05PM ET, Saturday)
• Royals vs. White Sox (4:10PM ET, Saturday)
• Astros vs. Guardians (4:10PM ET, Saturday)
• D-Backs vs. Reds (4:10PM ET, Saturday)
• Marlins vs. Rays (4:10PM ET, Saturday)
• Padres vs. Brewers (7:35PM ET, Saturday)
• Red Sox vs. Yankees (7:35PM ET, Saturday)
• Mariners vs. Angels (9:38PM ET, Saturday)
• Mets vs. Rockies (9:40PM ET, Saturday)

More on MLB

The best on this page form part of our MLB player props and MLB best bets series.

For more MLB betting content, we have MLB trends for every game, as well as daily MLB betting news and the latest World Series odds and predictions.

Conclusion

Our MLB best bets are locked and loaded for June 6, 2025, featuring plays such as Under 10.5 Runs in the Orioles vs. Athletics matchup. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate MLB insights quickly, with human oversight ensuring high editorial quality. Our predictions are sourced from current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.