Free MLB Picks Today: Tuesday's Best Bets Include Mariners vs. Athletics Play [5/6/2025]

MLB betting is back for another pulse-pounding slate on 5/6, and we're here to serve up our top picks for Tuesday's baseball action.

Today's MLB best bets come from a range of matchups, including the Mariners vs. Athletics game at 10:05PM ET, with this article updated throughout the day to highlight the most attractive upcoming games.

Led by a standout over/under play with an edge of 5.2%, these picks are based on advanced simulations and machine learning.

For unlimited access to everything Dimers has to offer on Tuesday, May 6, 2025—including our complete set of MLB picks and best bets—check out Dimers Pro.

List of MLB Best Bets Tonight [5/6, Updated: 10:01PM ET]

After diving deep into the numbers and running thousands of simulations, our independent predictive analytics model has figured out the best baseball bets for Tuesday, May 6, 2025.

We sort these picks by start times, reserving the highest edges and probabilities exclusively for Dimers Pro subscribers.

Mariners vs. Athletics Under 10.5 Runs (-118)

• Edge: 5.2%
• Probability: 59.3%
• Matchup: Mariners vs. Athletics (10:05PM ET, Tuesday)

Our model has pinpointed the next MLB betting opportunity tonight, which comes in the Mariners vs. Athletics matchup. We recommend an over/under bet on Under 10.5 Runs at -118 odds, offering an edge of 5.2%.

Athletics ML (-120)

• Edge: 3.0%
• Probability: 57.6%
• Matchup: Mariners vs. Athletics (10:05PM ET, Tuesday)

Our model has found another great MLB bet for Tuesday's baseball action, again in the game between the Mariners and Athletics. We suggest placing a wager on Athletics ML at -120 odds, with our analysis showing a compelling 3.0% edge.

MORE: MLB Props

Athletics -1.5 (+162)

• Edge: 2.8%
• Probability: 40.9%
• Matchup: Mariners vs. Athletics (10:05PM ET, Tuesday)

Our next pick for Tuesday's baseball action is also from the Mariners vs. Athletics matchup. We recommend a run line bet on Athletics -1.5 at +162 odds. Our model suggests a favorable 2.8% edge for this wager.

MORE: Tuesday's MLB Trends

MLB Best Bets: Tuesday, 5/6/2025

As of 10:01PM ET, here are the next three MLB bets recommended by our model:

Matchup	Bet	Odds	Edge
Mariners vs. Athletics	Under 10.5 Runs	-118 @ DraftKings	5.2%
Mariners vs. Athletics	Athletics ML	-120 @ BetMGM	3.0%
Mariners vs. Athletics	Athletics -1.5	+162 @ FanDuel	2.8%

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While the bets listed are all positive expected value (+EV) opportunities, subscribing to Dimers Pro grants you instant access to today's best bets across all sports, powered by our advanced model.

Tuesday's full suite of MLB picks is highlighted by a run line opportunity with a substantial 5.7% edge over the sportsbook odds.

Join Dimers Pro now to access these picks, along with a comprehensive range of props, trends and parlays for May 6, 2025.

List of Upcoming MLB Games to Bet On [5/6/2025]

• Mariners vs. Athletics (10:05PM ET, Tuesday)
• Astros vs. Brewers (1:10PM ET, Wednesday)
• Pirates vs. Cardinals (1:15PM ET, Wednesday)
• Giants vs. Cubs (2:20PM ET, Wednesday)
• Mariners vs. Athletics (3:35PM ET, Wednesday)
• Mets vs. D-Backs (3:40PM ET, Wednesday)
• Dodgers vs. Marlins (4:40PM ET, Wednesday)
• Rangers vs. Red Sox (6:45PM ET, Wednesday)
• Padres vs. Yankees (7:05PM ET, Wednesday)
• Phillies vs. Rays (7:05PM ET, Wednesday)
• Reds vs. Braves (7:15PM ET, Wednesday)
• White Sox vs. Royals (7:40PM ET, Wednesday)
• Tigers vs. Rockies (8:40PM ET, Wednesday)
• Blue Jays vs. Angels (9:38PM ET, Wednesday)

More About MLB

This article is part of our MLB player props and MLB best bets series.

For more MLB betting content, we have MLB trends for every game, as well as daily MLB betting news and the latest World Series odds and predictions.

Conclusion

This article, enhanced by AI and automation, aims to deliver accurate MLB insights quickly, with human oversight ensuring high editorial quality. Our predictions are drawn from current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.