Free MLB Picks Today: Friday's MLB Best Bets Include Angels vs. Dodgers Play [5/16/2025]

Another action-packed MLB slate is on deck for 5/16, and we've locked in our free MLB picks for today and MLB best bets today to help you cash in on Friday's action.

Today's MLB best bets include matchups like Angels vs. Dodgers and Athletics vs. Giants, with this article updated throughout the day to feature the highest-probability plays based on thousands of data-driven simulations from our predictive analytics model.

But if you're serious about long-term profit, it's not just about probability—it's about edge. To unlock our highest-edge MLB bets—the ones with true long-term value—join Dimers Pro.

Pro members get unlimited access to everything Dimers has to offer on Friday, May 16, 2025, including our full suite of MLB picks and best bets.

List of MLB Best Bets Tonight [5/16, Updated 10:00PM ET]

After crunching the numbers and conducting thousands of simulations, our famous predictive analytics model has identified the best baseball bets for Friday, May 16, 2025.

While these free MLB picks for today are sorted by probability, the real edge—the bets with the highest long-term value—is reserved for Dimers Pro subscribers. Because smart betting isn't just about what's likely—it's about what's profitable.

Angels +1.5 (+140)

• Probability: 44.9%
• Edge: 3.2%
• Matchup: Angels vs. Dodgers (10:10PM ET, Friday)

Our model has pinpointed a high-probability MLB betting opportunity tonight, which comes in the Angels vs. Dodgers game. We recommend a run line bet on Angels +1.5 at +140 odds, with our analysis showing a 44.9% chance of hitting and a compelling edge of 3.2%.

Athletics ML (+170)

• Probability: 39.5%
• Edge: 2.4%
• Matchup: Athletics vs. Giants (10:15PM ET, Friday)

Our model has found another strong MLB bet for Friday's baseball action, this time in the matchup between the Athletics and Giants. We suggest placing a wager on Athletics ML at +170 odds, with a 39.5% probability delivering a 2.4% edge.

MORE: MLB Props

MLB Best Bets: Friday, 5/16/2025

As of 10:00PM ET, here are our top two MLB bets by probability recommended by our model:

Matchup	Bet	Odds	Probability	Edge
Angels vs. Dodgers	Angels +1.5	+140 @ DraftKings	44.9%	3.2%
Athletics vs. Giants	Athletics ML	+170 @ DraftKings	39.5%	2.4%

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The bets listed here are sorted by win probability—but the real path to profit lies in high-edge plays. Dimers Pro unlocks instant access to the most valuable bets across all sports, powered by our advanced predictive model.

Among today's MLB picks is a +140 run line bet with a 4.3% edge—the kind of high-upside play that makes a difference over time.

Join Dimers Pro now to access these picks, as well as a comprehensive range of props, trends and parlays for May 16, 2025.

List of Upcoming MLB Games to Bet On [5/16/2025]

• Angels vs. Dodgers (10:10PM ET, Friday)
• Athletics vs. Giants (10:15PM ET, Friday)
• Mets vs. Yankees (1:05PM ET, Saturday)
• White Sox vs. Cubs (2:20PM ET, Saturday)
• Nationals vs. Orioles (4:05PM ET, Saturday)
• Rays vs. Marlins (4:10PM ET, Saturday)
• Pirates vs. Phillies (6:05PM ET, Saturday)
• Guardians vs. Reds (6:40PM ET, Saturday)
• Astros vs. Rangers (7:05PM ET, Saturday)
• Cardinals vs. Royals (7:10PM ET, Saturday)
• Braves vs. Red Sox (7:15PM ET, Saturday)
• Twins vs. Brewers (7:15PM ET, Saturday)
• Rockies vs. D-Backs (8:10PM ET, Saturday)
• Mariners vs. Padres (8:40PM ET, Saturday)
• Athletics vs. Giants (9:05PM ET, Saturday)
• Angels vs. Dodgers (9:10PM ET, Saturday)

More on MLB

The best on this page form part of our MLB player props and MLB best bets series.

For more MLB betting content, we have MLB trends for every game, as well as daily MLB betting news and the latest World Series odds and predictions.

Conclusion

Our MLB best bets are locked and loaded for May 16, 2025, featuring plays such as Angels +1.5 and Athletics ML. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate MLB insights quickly, with human oversight ensuring high editorial quality. Our predictions are based on current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.