Free MLB picks today: Wednesday's MLB best bets include Giants vs. Padres play [8/20/2025]

Today’s free MLB picks for August 20, 2025 are here, with Wednesday’s MLB best bets fueled by tens of thousands of predictive simulations analyzing the latest odds and matchups.

These MLB best bets include matchups like the Giants vs. Padres game at 9:40PM ET, with this article updated throughout the day to feature the highest-probability plays based on thousands of data-driven simulations from our predictive analytics model.

But if you're serious about long-term profit, it's not just about probability—it's about edge. To unlock our highest-edge MLB bets—the ones with true long-term value—join Dimers Pro.

Pro members get unlimited access to everything Dimers has to offer on Wednesday, August 20, 2025, including our complete set of picks and best bets for today and the week ahead.

List of MLB best bets tonight [8/20, updated 9:31PM ET]

After crunching the numbers and running thousands of simulations, our famous predictive analytics model has identified the best baseball bets for Wednesday, August 20, 2025.

Padres ML (-134)

• Probability: 60.1%
• Edge: 2.6%
• matchup: Giants vs. Padres (9:40PM ET, Wednesday)

Our model has pinpointed a high-probability MLB betting opportunity tonight, which comes in the Giants vs. Padres game. We recommend a bet on the Padres ML at -134 odds, with our analysis showing a 60.1% chance of hitting and a compelling edge of 2.6%.

Padres -1.5 (+155)

• Probability: 41.3%
• Edge: 2.1%
• matchup: Giants vs. Padres (9:40PM ET, Wednesday)

Our model has found another strong MLB bet for Wednesday's baseball action, again in the game between the Giants and Padres. We suggest placing a run line wager on Padres -1.5 at +155 odds, with a 41.3% probability delivering a 2.1% edge.

MLB best bets: Wednesday, 8/20/2025

As of 9:31PM ET, here are our top two MLB bets by probability recommended by our model:

The bets listed here are sorted by win probability—but the real path to profit lies in high-edge plays. Dimers Pro unlocks instant access to the most valuable bets across all sports, powered by our advanced predictive model.

Among today's MLB picks is a +170 run line bet with a 6.2% edge—the kind of high-upside play that makes a difference over time.

Join Dimers Pro now to access these picks, as well as a comprehensive range of props, trends and parlays for August 20, 2025.

List of Upcoming MLB Games to Bet On [8/20/2025]

• Reds vs. Angels (9:38PM ET, Wednesday)
• Giants vs. Padres (9:40PM ET, Wednesday)
• Rangers vs. Royals (2:10PM ET, Thursday)
• Brewers vs. Cubs (2:20PM ET, Thursday)
• Dodgers vs. Rockies (3:10PM ET, Thursday)
• Mets vs. Nationals (4:05PM ET, Thursday)
• Giants vs. Padres (4:10PM ET, Thursday)
• Astros vs. Orioles (7:15PM ET, Thursday)
• Red Sox vs. Yankees (7:15PM ET, Thursday)
• Cardinals vs. Rays (7:35PM ET, Thursday)

More about MLB

The best on this page form part of our MLB player props and MLB best bets series.

For more MLB betting content, we have MLB trends for every game, as well as daily MLB betting news and the latest World Series odds and predictions.

Conclusion

Our MLB best bets are locked and loaded for August 20, 2025, featuring plays such as Padres ML and Padres -1.5. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate MLB insights quickly, with human oversight ensuring high editorial quality. Our predictions are rooted in current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

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