Free MLB picks today: Thursday's MLB best bets include two run line plays [9/18/2025]

Today’s free MLB picks for September 18, 2025 are here, with Thursday’s MLB best bets backed by tens of thousands of data simulations analyzing the latest odds and matchups.

These MLB best bets include matchups like Angels vs. Brewers and Yankees vs. Orioles, with this article updated throughout the day to feature the highest-probability plays based on thousands of data-driven simulations from our predictive analytics model.

But if you're serious about long-term profit, it's not just about probability—it's about edge. To unlock our highest-edge MLB bets—the ones with true long-term value—join Dimers Pro.

Pro members get unlimited access to everything Dimers has to offer on Thursday, September 18, 2025, including our full set of picks and best bets for today and the week ahead.

List of MLB best bets tonight [9/18, updated 6:01PM ET]

After crunching the numbers and running thousands of simulations, our leading predictive analytics model has figured out the best baseball bets for Thursday, September 18, 2025.

Angels +1.5 (-102)

• Probability: 55.2%
• Edge: 4.7%
• Matchup: Angels vs. Brewers (7:40PM ET, Thursday)

Our model has pinpointed a high-probability MLB betting opportunity tonight, which comes in the Angels vs. Brewers game. We recommend a run line bet on Angels +1.5 at -102 odds, with our analysis showing a 55.2% chance of hitting and a compelling edge of 4.7%.

Orioles +1.5 (+108)

• Probability: 50.2%
• Edge: 2.2%
• Matchup: Yankees vs. Orioles (7:15PM ET, Thursday)

Our model has found another strong MLB bet for Thursday's baseball action, this time in the game between the Yankees and Orioles. We suggest placing a run line wager on Orioles +1.5 at +108 odds, with a 50.2% probability delivering a 2.2% edge.

Orioles ML (+176)

• Probability: 38.5%
• Edge: 2.3%
• Matchup: Yankees vs. Orioles (7:15PM ET, Thursday)

Our model has found another strong MLB bet for Thursday's baseball action, also in the Yankees vs. Orioles game. We recommend a bet on Orioles ML at +176 odds. Our projections shows a 38.5% probability and 2.3% edge for this wager.

MLB best bets: Thursday, 9/18/2025

As of 6:01PM ET, here are our top three MLB bets by probability recommended by our model:

Matchup	Bet	Odds	Probability	Edge
Angels vs. Brewers	Angels +1.5	-102 @ DraftKings	55.2%	4.7%
Yankees vs. Orioles	Orioles +1.5	+108 @ DraftKings	50.2%	2.2%
Yankees vs. Orioles	Orioles ML	+176 @ DraftKings	38.5%	2.3%

Dimers Pro unlocks instant access to the most valuable bets across all sports, powered by our advanced predictive model.

Today, Dimers Pro subscribers have access to four MLB picks—with access to all of these being what makes a difference over time.

Join Dimers Pro now to access these picks, as well as a comprehensive range of props, trends and parlays for September 18, 2025.

List of upcoming MLB games to bet on [9/18/2025]

• Yankees vs. Orioles (7:15PM ET, Thursday)
• Cubs vs. Reds (7:15PM ET, Thursday)
• Angels vs. Brewers (7:40PM ET, Thursday)
• Giants vs. Dodgers (10:10PM ET, Thursday)

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More on MLB

The bets on this page form part of our MLB player props and MLB best bets series.

For more MLB betting content, we have MLB trends for every game, as well as daily MLB betting news and the latest World Series odds and predictions.

Conclusion

Our MLB best bets are locked and loaded for September 18, 2025, featuring plays such as Angels +1.5 and Orioles +1.5. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate MLB insights quickly, with human oversight ensuring high editorial quality. Our predictions are grounded in current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

All odds and probabilities in this article are correct and accurate at the time of publication.

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