Free MLB picks today: Wednesday's MLB best bets revealed after 10,000 simulations [9/10/2025]

Today’s free MLB picks for September 10, 2025 are here, with Wednesday’s MLB best bets powered by tens of thousands of predictive simulations analyzing the latest odds and matchups.

Today's MLB best bets will be sourced from matchups such as Cardinals vs. Mariners, with this article updated throughout the day to feature the highest-probability plays based on thousands of data-driven simulations from our predictive analytics model.

Pro members get unlimited access to everything Dimers has to offer, including our full set of picks and best bets for today and the week ahead.

List of MLB best bets today [9/10, updated 9:31PM ET]

After simulating today's remaining MLB action thousands of times, our model has concluded that there are no MLB bets worth making right now. This is due to the lack of valuable edges between our data-driven probabilities and the best available odds.

List of upcoming MLB games to bet on [9/10/2025]

• Cardinals vs. Mariners (9:40PM ET, Wednesday)
• Rockies vs. Dodgers (10:10PM ET, Wednesday)
• Pirates vs. Orioles (1:05PM ET, Thursday)
• Rays vs. White Sox (2:10PM ET, Thursday)
• Astros vs. Blue Jays (3:07PM ET, Thursday)
• Nationals vs. Marlins (6:40PM ET, Thursday)
• Royals vs. Guardians (7:15PM ET, Thursday)
• Mets vs. Phillies (7:15PM ET, Thursday)

More on MLB

The bets on this page form part of our MLB player props and MLB best bets series.

For more MLB betting content, we have MLB trends for every game, as well as daily MLB betting news and the latest World Series odds and predictions.

Conclusion

Our MLB best bets are locked and loaded for September 10, 2025, with our in-house predictive analytics model constantly searching for bets across Wednesday's action.. Powered by advanced simulations, these picks are here to boost your betting game.

This article, enhanced by AI and automation, aims to deliver accurate MLB insights quickly, with human oversight ensuring high editorial quality. Our predictions are rooted in current data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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