Minnesota Vikings vs. Pittsburgh Steelers early prediction: Expert picks for NFL Week 4, 2025

The Minnesota Vikings and Pittsburgh Steelers will meet in Week 4 of the NFL season at Croke Park on Sunday, September 28, 2025, starting at 9:30AM ET.

Early simulations from Dimers' trusted NFL model favor the Vikings as the most likely winner of this matchup.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Vikings vs. Steelers predictions page.

Minnesota vs. Pittsburgh early predictions

Leveraging trusted machine learning and analysis, we have simulated the Vikings vs. Steelers game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Vikings 60%, Steelers 40%
• Predicted final score: Vikings 22-19 Steelers
• Spread: Vikings (-1.5) 53%, Steelers (+1.5) 47%
• Total points (42.5): Over 46%, Under 54%

As of September 21, 2025, these Vikings-Steelers numbers and predictions reflect the latest data and insights available.

Vikings vs. Steelers Week 4 details

The NFL Week 4 game between the Steelers and Vikings at Croke Park is scheduled for September 28, 2025.

• Who: Minnesota Vikings vs. Pittsburgh Steelers
• Date: Sunday, September 28, 2025
• Time: 9:30AM ET/6:30AM PT
• Venue: Croke Park

Vikings vs. Steelers opening odds

We've researched the best betting odds across America for this Week 4 game, which are listed here:

• Spread: Vikings -1.5 (-110), Steelers +1.5 (-110)
• Moneyline: Vikings -120, Steelers +108
• Total: Over/Under 42.5 (-110/-110)

Odds may continue to move—track live changes via our NFL odds page.

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Conclusion

We predict the Vikings, with a 60% win probability, will likely beat the Steelers in Week 4 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Vikings vs. Steelers matchup, with human oversight maintaining high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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