Minnesota Vikings vs. Cleveland Browns early prediction: Expert picks for NFL Week 5, 2025

The Minnesota Vikings and Cleveland Browns will meet in Week 5 of the NFL season at Tottenham Hotspur Stadium on Sunday, October 5, 2025, starting at 9:30AM ET.

Early simulations from Dimers' trusted NFL model favor the Vikings as the most likely winner of this matchup.

For updates all week long, including best bets, player prop projections and touchdown probabilities, check out our interactive Vikings vs. Browns predictions page.

Minnesota vs. Cleveland early predictions

Leveraging trusted machine learning and analysis, we have simulated the Vikings vs. Browns game 10,000 times as part of our NFL predictions coverage. Here are the latest insights:

• Straight up win probabilities: Vikings 78%, Browns 22%
• Predicted final score: Vikings 24-17 Browns
• Spread: Vikings (-6.5) 54%, Browns (+6.5) 46%
• Total points (40.5): Over 53%, Under 47%

As of September 28, 2025, these Vikings-Browns figures and predictions reflect the latest data and insights available.

Vikings vs. Browns Week 5 details

The NFL Week 5 game between the Browns and Vikings at Tottenham Hotspur Stadium is scheduled for October 5, 2025.

• Who: Minnesota Vikings vs. Cleveland Browns
• Date: Sunday, October 5, 2025
• Time: 9:30AM ET/6:30AM PT
• Venue: Tottenham Hotspur Stadium

Vikings vs. Browns opening odds

We've researched the best betting odds across America for this Week 5 game, which are listed here:

• Spread: Vikings -6.5 (-120), Browns +6.5 (+100)
• Moneyline: Vikings -325, Browns +280
• Total: Over/Under 40.5 (-105/-115)

Odds may continue to move—track live changes via our NFL odds page.

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Conclusion

We predict the Vikings, with a 78% win probability, will likely beat the Browns in Week 5 of the NFL season. Dimers.com will provide full game coverage closer to kickoff, so stay tuned for updates.

Enhanced by AI and automation, this article delivers quick, accurate insights on the Vikings vs. Browns matchup, with human oversight maintaining high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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