Twins vs. Phillies prediction: Why Philadelphia is favored to win Sunday's MLB matchup [9/28/2025]

The Philadelphia Phillies will square off with the Minnesota Twins in MLB action at Citizens Bank Park on Sunday, beginning at 3:05PM ET.

Cristopher Sánchez (13-5, 2.57 ERA) will start for the Phillies, up against Simeon Woods Richardson (7-4, 4.27 ERA) for the Twins.

Based on updated simulations, Dimers' proven MLB model projects the Phillies as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Twins-Phillies game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Phillies with a win probability of 72%, while the Twins have 28%."

For expanded analysis of Sunday's matchup, including best bets and picks, visit our interactive Twins vs. Phillies predictions page.

Phillies vs. Twins prediction: Who will win, cover the run line?

Using innovative machine learning and statistical analysis, we have simulated the result of Sunday's MLB matchup between the Twins and Phillies 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Phillies a 72% chance of defeating the Twins.

According to our model, the Phillies (-1.5) have a 54% chance of covering the run line, while the 8-run over/under has a 62% chance of going over.

Twins vs. Phillies odds [9/28/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Twins	Phillies
Run Line	+1.5 (+102)	-1.5 (-115)
Moneyline	+205	-250
Total	o8 (-118)	u8 (-104)

All odds are correct at the time of publication and are subject to change.

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Twins vs. Phillies picks and best bets

Our model's strongest edge in today's Twins vs. Phillies matchup is on the run line.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets

Calling Our Shot produces daily MLB betting content, including the predictions featured below.

Twins vs. Phillies game-day updates and essential details

Sunday's MLB action between the Phillies and Twins at Citizens Bank Park is scheduled to begin at 3:05PM ET.

• Who: Minnesota Twins vs. Philadelphia Phillies
• Date: Sunday, September 28, 2025
• Time: 3:05PM ET/12:05PM PT
• Venue: Citizens Bank Park

Dimers' full preview of Sunday's Twins vs. Phillies matchup includes our prediction, picks and the latest betting odds.

Before making any Twins vs. Phillies picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Phillies, with a 72% win probability, will likely beat the Twins on Sunday.

AI and automation have enhanced this article to quickly deliver accurate Twins vs. Phillies insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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