Twins vs. Brewers Prediction: Minnesota Predicted to Win Friday's MLB Matchup [5/16/2025]

The Milwaukee Brewers and Minnesota Twins are scheduled to meet in MLB action at American Family Field on Friday, starting at 8:10PM ET.

The Brewers will have Chad Patrick (2-3, 3.19 ERA) as their starting pitcher, while the Twins will counter with Joe Ryan (3-2, 2.74 ERA).

Based on the latest simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Twins as the most likely winner of today's game.

"Employing the latest data, our experts simulated Friday's Minnesota-Milwaukee game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"After computing the latest updates and thousands of other inputs, we predict the Twins' chance of winning is 53%, while the Brewers' is 47%."

For a closer look at Friday's matchup, including best bets and picks, visit our interactive Twins vs. Brewers predictions page.

Brewers vs. Twins Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data, we have simulated the result of Friday's MLB matchup between the Twins and Brewers 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Twins a 53% chance of beating the Brewers.

According to our model, the Brewers (+1.5) have a 61% chance of covering the run line, while the 7.5-run over/under has a 52% chance of going over.

Twins vs. Brewers Odds [5/16/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Twins	Brewers
Run Line	-1.5 (+145)	+1.5 (-172)
Moneyline	-115	+102
Total	o7.5 (-110)	u7.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Twins vs. Brewers Picks and Best Bets

Our model's strongest edge in today's Twins vs. Brewers matchup is on the run line.

Our expert predictions, matched against the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Twins vs. Brewers Game-Day Updates and Essential Details

Friday's MLB action between the Brewers and Twins at American Family Field is scheduled to start at 8:10PM ET.

• Who: Minnesota Twins vs. Milwaukee Brewers
• Date: Friday, May 16, 2025
• Time: 8:10PM ET/5:10PM PT
• Venue: American Family Field

Dimers.com's comprehensive preview of Friday's Twins vs. Brewers matchup includes our prediction, picks and the latest betting odds.

Before making any Minnesota vs. Milwaukee picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Twins, with a 53% win probability, will likely beat the Brewers on Friday.

AI and automation have enhanced this article to quickly deliver accurate Twins vs. Brewers insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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