Twins vs. Dodgers Prediction: Dodgers Predicted to Win Monday's MLB Matchup [7/21/2025]

MLB action continues on Monday at 10:10PM ET as the Minnesota Twins take on the Los Angeles Dodgers at Dodger Stadium.

Shohei Ohtani (0-0, 1.00 ERA) will get the ball for the Dodgers, while the Twins are going with David Festa (3-3, 5.25 ERA).

Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Dodgers as the most likely winner of today's game.

For a closer look at Monday's matchup, including best bets and picks, visit our interactive Twins vs. Dodgers predictions page.

Dodgers vs. Twins Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data, we have simulated the outcome of Monday's MLB matchup between the Twins and Dodgers 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Dodgers a 61% chance of defeating the Twins.

According to our model, the Twins (+1.5) have a 56% chance of covering the run line, while the over/under total of 9 runs has a 55% chance of staying under.

Twins vs. Dodgers Odds [7/21/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Twins	Dodgers
Run Line	+1.5 (-126)	-1.5 (+108)
Moneyline	+160	-181
Total	o9 (+100)	u9 (-118)

All odds are correct at the time of publication and are subject to change.

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Twins vs. Dodgers Picks and Best Bets

Our model's strongest edge in today's Twins vs. Dodgers matchup is on the moneyline.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the best bets featured below.

Twins vs. Dodgers Game-Day Updates and Essential Details

Monday's MLB game between the Dodgers and Twins at Dodger Stadium is scheduled to start at 10:10PM ET.

• Who: Minnesota Twins vs. Los Angeles Dodgers
• Date: Monday, July 21, 2025
• Time: 10:10PM ET/7:10PM PT
• Venue: Dodger Stadium

Dimers.com's in-depth preview of Monday's Twins vs. Dodgers matchup includes our prediction, picks and the latest betting odds.

Before making any Twins vs. Dodgers picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Dodgers, with a 61% win probability, will likely beat the Twins on Monday.

AI and automation have enhanced this article to quickly deliver accurate Twins vs. Dodgers insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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