Twins vs. Tigers Prediction: Detroit Predicted to Win Saturday's MLB Matchup [6/28/2025]

The Detroit Tigers will take on the Minnesota Twins in MLB action at Comerica Park on Saturday, beginning at 1:10PM ET.

Casey Mize (7-2, 2.88 ERA) will start on the mound for the Tigers, while the Twins have opted for Bailey Ober (4-5, 4.90 ERA).

Based on the latest simulations, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Tigers as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's Twins-Tigers game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that the Tigers are more likely to win, while the Twins have a lower chance of victory."

For expanded analysis of Saturday's matchup, including best bets and picks, visit our interactive Twins vs. Tigers predictions page.

Tigers vs. Twins Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data, we have simulated the outcome of Saturday's MLB game between the Twins and Tigers 10,000 times as part of our MLB predictions coverage.

Our leading predictive model currently gives the Tigers a 56% chance of defeating the Twins.

According to our model, the Twins (+1.5) have a 61% chance of covering the run line, while the over/under total of 9 runs has an equal 50-50 chance of hitting.

Twins vs. Tigers Odds [6/28/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Twins	Tigers
Run Line	+1.5 (-151)	-1.5 (+128)
Moneyline	+136	-160
Total	o9 (-113)	u9 (-105)

All odds are correct at the time of publication and are subject to change.

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Twins vs. Tigers Picks and Best Bets

Our model's strongest edge in today's Twins vs. Tigers matchup is on the moneyline.

Our expert predictions, matched against the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Twins vs. Tigers Game-Day Updates and Essential Details

Saturday's MLB game between the Tigers and Twins at Comerica Park is scheduled to begin at 1:10PM ET.

• Who: Minnesota Twins vs. Detroit Tigers
• Date: Saturday, June 28, 2025
• Time: 1:10PM ET/10:10AM PT
• Venue: Comerica Park

Dimers.com's comprehensive preview of Saturday's Twins vs. Tigers matchup includes our prediction, picks and the latest betting odds.

Before making any Twins vs. Tigers picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Tigers, with a 56% win probability, will likely beat the Twins on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Twins vs. Tigers insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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