Brewers vs. Cardinals Prediction: St. Louis Predicted to Win Saturday's MLB Matchup [4/26/2025]

The St. Louis Cardinals and Milwaukee Brewers are scheduled to meet in MLB action at Busch Stadium on Saturday, starting at 2:15PM ET.

The Cardinals will start Sonny Gray (3-0, 3.41 ERA), while the Brewers are going with Quinn Priester (1-0, 1.93 ERA).

Based on updated simulation results, Dimers' proven MLB model (see Dimers Pro for full access) predicts the Cardinals as the most likely winner of today's game.

"Our team has used the latest data to run 10,000 simulations of Saturday's Milwaukee-St. Louis game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that the Cardinals are more likely to win, while the Brewers have a lower chance of victory."

For further insights into Saturday's matchup, including best bets and picks, visit our interactive Brewers vs. Cardinals predictions page.

Cardinals vs. Brewers Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and statistical analysis, we have simulated the result of Saturday's MLB game between the Brewers and Cardinals 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Cardinals a 58% chance of defeating the Brewers.

According to our model, the Brewers (+1.5) have a 61% chance of covering the run line, while the over/under total of 7 runs has a 52% chance of going over.

Brewers vs. Cardinals Odds [4/26/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Brewers	Cardinals
Run Line	+1.5 (-166)	-1.5 (+155)
Moneyline	+126	-148
Total	o7 (-120)	u7 (+105)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Brewers vs. Cardinals Picks and Best Bets

Our model's biggest edge in today's Brewers vs. Cardinals matchup is on the over/under.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Today

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Brewers vs. Cardinals Game-Day Updates and Essential Details

Saturday's MLB action between the Cardinals and Brewers at Busch Stadium is scheduled to start at 2:15PM ET.

• Who: Milwaukee Brewers vs. St. Louis Cardinals
• Date: Saturday, April 26, 2025
• Time: 2:15PM ET/11:15AM PT
• Venue: Busch Stadium

Dimers.com's full preview of Saturday's Brewers vs. Cardinals matchup includes our prediction, picks and the latest betting odds.

Before making any Milwaukee vs. St. Louis picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

• Explore how MLB odds work and dive into MLB live betting strategies
• Understand where sports odds come from and how they're applied to baseball matchups
• Learn how to use Dimers Futures to find long-term betting opportunities as the World Series draws closer
• Stay informed with where online sports betting is currently legal and which betting sites are safest to use
• Boost your success with strategies to win at sports betting and explore why MLB is one of the best leagues to bet on

Sports Betting Deals Available for Saturday

To make the most of Saturday's enormous day of sports, headlined by a huge day of NBA and NHL playoffs action, check out details on the latest Bet365 bonus code "DIMERS" that grants you the choice of two excellent signup promotions.

Plus, find out all the details on the BetMGM bonus code "DIMERS150" which is now available in New Jersey, Pennsylvania, Michigan, Colorado, and West Virginia. Don't miss out!

Conclusion

We predict the Cardinals, with a 58% win probability, will likely beat the Brewers on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Brewers vs. Cardinals insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Keep up with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds offer the latest probabilities for the World Series, American League, National League and each division.