Brewers vs. Cubs Prediction: Cubs Predicted to Win Wednesday's MLB Matchup [6/18/2025]

The Chicago Cubs will face the Milwaukee Brewers in MLB action at Wrigley Field on Wednesday, commencing at 8:05PM ET.

The Cubs will start Jameson Taillon (7-3, 3.48 ERA), while the Brewers have opted for Jacob Misiorowski (1-0, 0.00 ERA).

Based on updated simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Cubs as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Milwaukee-CHI Cubs game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Cubs' chance of winning at 57%, with the Brewers at 43%."

For expanded analysis of Wednesday's matchup, including best bets and picks, visit our interactive Brewers vs. Cubs predictions page.

Cubs vs. Brewers Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and data analysis, we have simulated the result of Wednesday's MLB matchup between the Brewers and Cubs 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Cubs a 57% chance of defeating the Brewers.

According to our model, the Brewers (+1.5) have a 62% chance of covering the run line, while the 8-run over/under has an equal 50-50 chance of hitting.

Brewers vs. Cubs Odds [6/18/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Brewers	Cubs
Run Line	+1.5 (-164)	-1.5 (+140)
Moneyline	+130	-150
Total	o8 (-105)	u8 (-110)

All odds are correct at the time of publication and are subject to change.

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Brewers vs. Cubs Picks and Best Bets

Our model's biggest edge in today's Brewers vs. Cubs matchup is on the over/under.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Today

Calling Our Shot produces daily MLB betting content, including the latest best bets featured below.

Brewers vs. Cubs Game-Day Updates and Essential Details

Wednesday's MLB matchup between the Cubs and Brewers at Wrigley Field is scheduled to begin at 8:05PM ET.

• Who: Milwaukee Brewers vs. Chicago Cubs
• Date: Wednesday, June 18, 2025
• Time: 8:05PM ET/5:05PM PT
• Venue: Wrigley Field

Dimers.com's in-depth preview of Wednesday's Brewers vs. Cubs matchup includes our prediction, picks and the latest betting odds.

Before making any Milwaukee vs. CHI Cubs picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

• Explore how MLB odds work and dive into MLB live betting strategies
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Conclusion

We predict the Cubs, with a 57% win probability, will likely beat the Brewers on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Brewers vs. Cubs insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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