Michigan vs. Nebraska prediction: Nebraska favored to win in college football Week 4, 2025

Nebraska and Michigan will meet in Week 4 college football action at Memorial Stadium on Saturday, beginning at 3:30PM ET.

Based on updated simulation results, Dimers' proven college football model predicts Nebraska as the most likely winner of today's game.

For expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Michigan vs. Nebraska predictions page.

Michigan vs. Nebraska prediction: Who will win, cover the spread?

Using powerful machine learning and data, we have simulated the result of Michigan vs. Nebraska 10,000 times as part of our college football predictions coverage.

Our independent predictive model gives Nebraska a 54% chance of beating Michigan. Our predicted final score has Nebraska winning 25-24.

According to our model, Nebraska (+1.5) has a 55% chance of covering the spread, while the over/under total of 47.5 points has a 55% chance of staying under.

Michigan vs. Nebraska odds

We have researched the best college football odds in America for this game, which are listed here:

Bet Type	Michigan	Nebraska
Spread	-1.5 (-105)	+1.5 (-112)
Moneyline	-110	-102
Total	o47.5 (-108)	u47.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Michigan vs. Nebraska picks and best bets

Our model's biggest edge in today's Michigan vs. Nebraska matchup is on the spread.

Our expert predictions, aligned with the current odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Michigan vs. Nebraska game-day updates and essential details

Saturday's college football matchup between Nebraska and Michigan at Memorial Stadium is scheduled to start at 3:30PM ET.

• Who: Michigan vs. Nebraska
• Date: Saturday, September 20, 2025
• Time: 3:30PM ET/12:30PM PT
• Venue: Memorial Stadium

Dimers' comprehensive preview of Saturday's Michigan vs. Nebraska matchup includes our prediction, picks and the latest betting odds.

Before making any Michigan vs. Nebraska picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Nebraska, with a 54% win probability, will likely beat Michigan on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Michigan vs. Nebraska insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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