Marlins vs. Nationals prediction: Why Miami is favored to win Wednesday's MLB matchup [9/3/2025]

The Washington Nationals will square off with the Miami Marlins, in what is expected to be a tight MLB game, at Nationals Park on Wednesday, beginning at 1:05PM ET.

The Nationals will send Mitchell Parker (7-15, 5.94 ERA) to the mound, while the Marlins will counter with Eury Pérez (6-4, 4.04 ERA).

Based on the latest simulation results, Dimers' proven MLB model predicts the Marlins as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Marlins-Nationals game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Marlins' chance of winning at 53%, with the Nationals at 47%."

For expanded analysis of Wednesday's matchup, including best bets and picks, visit our interactive Marlins vs. Nationals predictions page.

Nationals vs. Marlins prediction: Who will win, cover the run line?

Using powerful machine learning and data, we have simulated the outcome of Wednesday's MLB matchup between the Marlins and Nationals 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Marlins a 53% chance of defeating the Nationals.

According to our model, the Nationals (+1.5) have a 60% chance of covering the run line, while the over/under total of 9 runs has a 55% chance of staying under.

Marlins vs. Nationals odds [9/3/2025]

We have researched the best MLB odds in America for this game, which are listed here:

Bet Type	Marlins	Nationals
Run Line	-1.5 (+114)	+1.5 (-125)
Moneyline	-149	+128
Total	o9 (+100)	u9 (-113)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Marlins vs. Nationals picks and best bets

Our model's strongest edge in today's Marlins vs. Nationals matchup is on the total.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's best bets video

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Marlins vs. Nationals game-day updates and essential details

Wednesday's MLB action between the Nationals and Marlins at Nationals Park is scheduled to start at 1:05PM ET.

• Who: Miami Marlins vs. Washington Nationals
• Date: Wednesday, September 3, 2025
• Time: 1:05PM ET/10:05AM PT
• Venue: Nationals Park

Dimers.com's comprehensive preview of Wednesday's Marlins vs. Nationals matchup includes our prediction, picks and the latest betting odds.

Before making any Marlins vs. Nationals picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Marlins, with a 53% win probability, will likely beat the Nationals on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Marlins vs. Nationals insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Stay informed with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds offer the latest projections for the World Series, American League, National League and each division.