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Marlins vs. Cardinals Prediction: St. Louis Predicted to Win Wednesday's MLB Matchup [7/30/2025]

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Written by Dave Garofolo

Our expert prediction for Wednesday's Miami Marlins vs St. Louis Cardinals matchup.

Miami Marlins-St. Louis Cardinals Predictions and Game Preview.
Busch Stadium sets the stage for the MLB matchup between the Miami Marlins and St. Louis Cardinals this Wednesday.

The St. Louis Cardinals will face the Miami Marlins in MLB action at Busch Stadium on Wednesday, commencing at 7:45PM ET.

The Cardinals will send Miles Mikolas (6-7, 4.94 ERA) to the mound, while the Marlins will counter with Cal Quantrill (3-8, 5.05 ERA).

Based on updated simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Cardinals as the most likely winner of today's game. "Our team has simulated the outcome of Wednesday's Marlins-Cardinals game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Cardinals' chance of winning at 55%, with the Marlins at 45%."

For a closer look at Wednesday's matchup, including best bets and picks, visit our interactive Marlins vs. Cardinals predictions page.

Cardinals vs. Marlins Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and data, we have simulated the outcome of Wednesday's MLB game between the Marlins and Cardinals 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Cardinals a 55% chance of beating the Marlins.

According to our model, the Marlins (+1.5) have a 61% chance of covering the run line, while the 8.5-run over/under has an equal 50-50 chance of hitting.

 

Marlins vs. Cardinals Odds [7/30/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type Marlins Cardinals
Run Line +1.5 (-172) -1.5 (+152)
Moneyline +120 -134
Total o8.5 (-104) u8.5 (-115)

All odds are correct at the time of publication and are subject to change.

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Marlins vs. Cardinals Picks and Best Bets

Our model's strongest edge in today's Marlins vs. Cardinals matchup is on the run line.

Our expert predictions, matched against the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.

Marlins vs. Cardinals Game-Day Updates and Essential Details

Wednesday's MLB action between the Cardinals and Marlins at Busch Stadium is scheduled to begin at 7:45PM ET.

Dimers.com's in-depth preview of Wednesday's Marlins vs. Cardinals matchup includes our prediction, picks and the latest betting odds.

Before making any Marlins vs. Cardinals picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Plus, with sports betting in Missouri launching on December 1, 2025, Dimers is where smart bettors turn for the latest updates and the best pre-registration offers in MO.

Conclusion

We predict the Cardinals, with a 55% win probability, will likely beat the Marlins on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Marlins vs. Cardinals insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Stay up-to-date with the latest MLB news and MLB parlay picks throughout the season. Plus, our World Series odds provide the most up-to-date predictions for the World Series, American League, National League and each division.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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