Marlins vs. Giants Prediction: San Francisco Predicted to Win Wednesday's MLB Matchup [6/25/2025]

MLB action continues on Wednesday at 9:45PM ET as the Miami Marlins face off with the favored San Francisco Giants at Oracle Park.

Logan Webb (7-5, 2.49 ERA) will get the ball for the Giants, while the Marlins will counter with Edward Cabrera (2-2, 3.81 ERA).

Based on the latest simulations, Dimers' advanced MLB model (see Dimers Pro for full access) projects the Giants as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Marlins-Giants game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Giants' chance of winning at 63%, with the Marlins at 37%."

For further insights into Wednesday's matchup, including best bets and picks, visit our interactive Marlins vs. Giants predictions page.

Giants vs. Marlins Prediction: Who Will Win, Cover the Run Line?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Wednesday's MLB matchup between the Marlins and Giants 10,000 times as part of our MLB predictions coverage.

Our famous predictive model gives the Giants a 63% chance of defeating the Marlins.

According to our model, the Marlins (+1.5) have a 56% chance of covering the run line, while the 6.5-run over/under has a 55% chance of going over.

Marlins vs. Giants Odds [6/25/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Marlins	Giants
Run Line	+1.5 (-114)	-1.5 (+101)
Moneyline	+194	-225
Total	o6.5 (-115)	u6.5 (+100)

All odds are correct at the time of publication and are subject to change.

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Marlins vs. Giants Picks and Best Bets

Our model's strongest edge in today's Marlins vs. Giants matchup is on the over/under.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets Video

Calling Our Shot produces daily MLB betting content, including the latest free picks featured below.

Marlins vs. Giants Game-Day Updates and Essential Details

Wednesday's MLB matchup between the Giants and Marlins at Oracle Park is scheduled to start at 9:45PM ET.

• Who: Miami Marlins vs. San Francisco Giants
• Date: Wednesday, June 25, 2025
• Time: 9:45PM ET/6:45PM PT
• Venue: Oracle Park

Dimers.com's full preview of Wednesday's Marlins vs. Giants matchup includes our prediction, picks and the latest betting odds.

Before making any Marlins vs. Giants picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Giants, with a 63% win probability, will likely beat the Marlins on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Marlins vs. Giants insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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