Marlins vs. Padres Prediction: San Diego Predicted to Win Tuesday's MLB Matchup [5/27/2025]

The San Diego Padres will face the Miami Marlins in MLB action at PETCO Park on Tuesday, beginning at 9:40PM ET.

Stephen Kolek (2-1, 2.84 ERA) will start for the Padres, up against Max Meyer (3-4, 4.15 ERA) for the Marlins.

Based on updated simulations, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Padres as the most likely winner of today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's Miami-San Diego game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various factors, our prediction shows the Padres with a win probability of 62%, compared to 38% for the Marlins."

For a closer look at Tuesday's matchup, including best bets and picks, visit our interactive Marlins vs. Padres predictions page.

Padres vs. Marlins Prediction: Who Will Win, Cover the Run Line?

Using innovative machine learning and data analysis, we have simulated the outcome of Tuesday's MLB game between the Marlins and Padres 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Padres a 62% chance of beating the Marlins.

According to our model, the Marlins (+1.5) have a 59% chance of covering the run line, while the 8-run over/under has a 52% chance of staying under.

Marlins vs. Padres Odds [5/27/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Marlins	Padres
Run Line	+1.5 (-155)	-1.5 (+140)
Moneyline	+142	-160
Total	o8 (-104)	u8 (-105)

All odds are correct at the time of publication and are subject to change.

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Marlins vs. Padres Picks and Best Bets

Our model's strongest edge in today's Marlins vs. Padres matchup is on the run line.

Our expert predictions, aligned with the current odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Free ⚾️ Picks

Calling Our Shot produces daily MLB betting content, including the latest predictions featured below.

Marlins vs. Padres Game-Day Updates and Essential Details

Tuesday's MLB matchup between the Padres and Marlins at PETCO Park is scheduled to begin at 9:40PM ET.

• Who: Miami Marlins vs. San Diego Padres
• Date: Tuesday, May 27, 2025
• Time: 9:40PM ET/6:40PM PT
• Venue: PETCO Park

Dimers.com's comprehensive preview of Tuesday's Marlins vs. Padres matchup includes our prediction, picks and the latest betting odds.

Before making any Miami vs. San Diego picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Key MLB Betting Guides and Insights

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Conclusion

We predict the Padres, with a 62% win probability, will likely beat the Marlins on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Marlins vs. Padres insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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