Marlins vs. Rockies prediction: Why Miami is favored to win Wednesday's MLB matchup [9/17/2025]

The Colorado Rockies and Miami Marlins will lock horns in MLB action at Coors Field on Wednesday, starting at 8:40PM ET.

McCade Brown (0-4, 9.88 ERA) will be the starting pitcher for the Rockies, pitting him against Ryan Weathers (2-1, 2.73 ERA) for the Marlins.

Based on updated simulations, Dimers' advanced MLB model predicts the Marlins as the most likely winner of today's game.

"Our team has simulated the outcome of Wednesday's Marlins-Rockies game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Marlins' chance of winning at 55%, with the Rockies at 45%."

For expanded analysis of Wednesday's matchup, including best bets and picks, visit our interactive Marlins vs. Rockies predictions page.

Rockies vs. Marlins prediction: Who will win, cover the run line?

Using innovative machine learning and data, we have simulated the outcome of Wednesday's MLB game between the Marlins and Rockies 10,000 times as part of our MLB predictions coverage.

Our famous predictive model currently gives the Marlins a 55% chance of beating the Rockies.

According to our model, the Rockies (+1.5) have a 57% chance of covering the run line, while the 10.5-run over/under has an equal 50-50 chance of hitting.

Marlins vs. Rockies odds [9/17/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Marlins	Rockies
Run Line	-1.5 (-110)	+1.5 (-110)
Moneyline	-160	+136
Total	o10.5 (-105)	u10.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Marlins vs. Rockies picks and best bets

Our model's biggest edge in today's Marlins vs. Rockies matchup is on the total.

Our expert predictions, aligned with the best odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Calling Our Shot's free MLB picks

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Marlins vs. Rockies game-day updates and essential details

Wednesday's MLB matchup between the Rockies and Marlins at Coors Field is scheduled to commence at 8:40PM ET.

• Who: Miami Marlins vs. Colorado Rockies
• Date: Wednesday, September 17, 2025
• Time: 8:40PM ET/5:40PM PT
• Venue: Coors Field

Dimers' in-depth preview of Wednesday's Marlins vs. Rockies matchup includes our prediction, picks and the latest betting odds.

Before making any Marlins vs. Rockies picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Marlins, with a 55% win probability, will likely beat the Rockies on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Marlins vs. Rockies insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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