Marlins vs. Guardians Prediction: Cleveland Predicted to Win Wednesday's MLB Matchup [8/13/2025]

The Cleveland Guardians and Miami Marlins will meet in MLB action at Progressive Field on Wednesday, starting at 6:40PM ET.

Gavin Williams (7-4, 3.17 ERA) will get the ball for the Guardians, while the Marlins are going with Eury Pérez (4-3, 3.25 ERA).

Based on updated simulation results, Dimers' advanced MLB model (see Dimers Pro for full access) predicts the Guardians as the most likely winner of today's game. "Our team has simulated the outcome of Wednesday's Marlins-Guardians game 10,000 times," said Dimers' Chief Content Officer, Nick Slade.

"With the latest updates and numerous other variables, we estimate the Guardians' chance of winning at 56%, with the Marlins at 44%."

For further insights into Wednesday's matchup, including best bets and picks, visit our interactive Marlins vs. Guardians predictions page.

Guardians vs. Marlins Prediction: Who Will Win, Cover the Run Line?

Using trusted machine learning and statistical analysis, we have simulated the outcome of Wednesday's MLB matchup between the Marlins and Guardians 10,000 times as part of our MLB predictions coverage.

Our independent predictive model gives the Guardians a 56% chance of beating the Marlins.

According to our model, the Marlins (+1.5) have a 63% chance of covering the run line, while the over/under total of 7.5 runs has a 53% chance of going over.

Marlins vs. Guardians Odds [8/13/2025]

We have sourced the best MLB odds in America for this game, which are listed here:

Bet Type	Marlins	Guardians
Run Line	+1.5 (-190)	-1.5 (+162)
Moneyline	+115	-131
Total	o7.5 (-115)	u7.5 (-105)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Marlins vs. Guardians Picks and Best Bets

Our model's strongest edge in today's Marlins vs. Guardians matchup is on the moneyline.

Our expert predictions, aligned with the latest odds, reveal the best MLB picks and MLB best bets for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Calling Our Shot's Best Bets

Calling Our Shot produces daily MLB betting content, including the free picks featured below.

Marlins vs. Guardians Game-Day Updates and Essential Details

Wednesday's MLB matchup between the Guardians and Marlins at Progressive Field is scheduled to commence at 6:40PM ET.

• Who: Miami Marlins vs. Cleveland Guardians
• Date: Wednesday, August 13, 2025
• Time: 6:40PM ET/3:40PM PT
• Venue: Progressive Field

Dimers.com's comprehensive preview of Wednesday's Marlins vs. Guardians matchup includes our prediction, picks and the latest betting odds.

Before making any Marlins vs. Guardians picks, be sure to check out the latest MLB predictions and betting advice from Dimers Pro.

Conclusion

We predict the Guardians, with a 56% win probability, will likely beat the Marlins on Wednesday.

AI and automation have enhanced this article to quickly deliver accurate Marlins vs. Guardians insights, with human oversight ensuring high editorial quality. Our predictions are sourced from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on MLB

Keep up with the latest MLB betting news and MLB parlay picks throughout the season. Plus, our World Series odds offer the latest projections for the World Series, American League, National League and each division.