Marshall vs. Middle Tennessee prediction: Why Marshall is favored to win in college football Week 4, 2025

Middle Tennessee and Marshall will clash in Week 4 college football action at Johnny "Red" Floyd Stadium on Saturday, commencing at 7:00PM ET.

Based on the latest simulations, Dimers' advanced college football model predicts Marshall as the most likely winner of today's game.

For expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Marshall vs. Middle Tennessee predictions page.

Marshall vs. Middle Tennessee prediction: Who will win, cover the spread?

Using powerful machine learning and data analysis, we have simulated the result of Marshall vs. Middle Tennessee 10,000 times as part of our college football predictions coverage.

Our independent predictive model currently gives Marshall a 51% chance of beating Middle Tennessee. Our predicted final score has Marshall winning 24-23.

According to our model, Middle Tennessee (+2.5) has a 54% chance of covering the spread, while the 46.5-point over/under has a 55% chance of staying under.

Marshall vs. Middle Tennessee odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type	Marshall	Middle Tennessee
Spread	-2.5 (-112)	+2.5 (-105)
Moneyline	-135	+115
Total	o46.5 (-110)	u46.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Marshall vs. Middle Tennessee picks and best bets

Our model's biggest edge in today's Marshall vs. Middle Tennessee matchup is on the spread.

Our expert predictions, aligned with the best odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Marshall vs. Middle Tennessee game-day updates and essential details

Saturday's college football action between Middle Tennessee and Marshall at Johnny "Red" Floyd Stadium is scheduled to begin at 7:00PM ET.

• Who: Marshall vs. Middle Tennessee
• Date: Saturday, September 20, 2025
• Time: 7:00PM ET/4:00PM PT
• Venue: Johnny "Red" Floyd Stadium

Dimers' in-depth preview of Saturday's Marshall vs. Middle Tennessee matchup includes our prediction, picks and the latest betting odds.

Before making any Marshall vs. Middle Tennessee picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict Marshall, with a 51% win probability, will likely beat Middle Tennessee on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Marshall vs. Middle Tennessee insights, with human oversight ensuring high editorial quality. Our predictions are drawn from the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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