Maine vs. William & Mary prediction: Why William & Mary is favored to win in college football Week 2, 2025

William & Mary will square off with Maine in Week 2 college football action at Walter J. Zable Stadium at Cary Field on Saturday, beginning at 6:00PM ET.

Based on the latest simulations, Dimers' proven college football model predicts William & Mary as the most likely winner of today's game.

For expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Maine vs. William & Mary predictions page.

Maine vs. William & Mary prediction: Who will win, cover the spread?

Using trusted machine learning and data, we have simulated the result of Maine vs. William & Mary 10,000 times as part of our college football predictions coverage.

Our famous predictive model currently gives William & Mary a 63% chance of beating Maine. Our predicted final score has William & Mary winning 26-21.

According to our model, Maine (+7.5) has a 60% chance of covering the spread, while the 48.5-point over/under has a 52% chance of staying under.

Maine vs. William & Mary odds

We have sourced the best college football odds in America for this game, which are listed here:

Bet Type	Maine	William & Mary
Spread	+7.5 (-115)	-7.5 (-105)
Moneyline	+210	-240
Total	o48.5 (-110)	u48.5 (-110)

All odds are correct at the time of publication and are subject to change.

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Maine vs. William & Mary picks and best bets

Our model's biggest edge in today's Maine vs. William & Mary matchup is on the total.

Our expert predictions, aligned with the current odds, reveal the best college football picks and college football best bets for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Maine vs. William & Mary game-day updates and essential details

Saturday's college football action between William & Mary and Maine at Walter J. Zable Stadium at Cary Field is scheduled to begin at 6:00PM ET.

• Who: Maine vs. William & Mary
• Date: Saturday, September 6, 2025
• Time: 6:00PM ET/3:00PM PT
• Venue: Walter J. Zable Stadium at Cary Field

Dimers.com's full preview of Saturday's Maine vs. William & Mary matchup includes our prediction, picks and the latest betting odds.

Before making any Maine vs. William & Mary picks, be sure to check out the latest college football predictions and betting advice from Dimers Pro.

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Conclusion

We predict William & Mary, with a 63% win probability, will likely beat Maine on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Maine vs. William & Mary insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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