Luciano Darderi vs. Eliot Spizzirri prediction, odds, picks for US Open 2025

Luciano Darderi will take on Eliot Spizzirri in the second round of the US Open Men's Singles 2025 on Wednesday.

Based on the latest simulation results, Dimers' advanced tennis model predicts Luciano Darderi as the most likely winner of the match.

"We have simulated the outcome of Wednesday's Darderi-Spizzirri match 10,000 times," said Dimers data analyst Greg Butyn.

"With the latest updates and numerous other variables, we estimate Luciano Darderi's chance of winning at 59%, with Eliot Spizzirri at 41%."

For a closer look at Wednesday's match, including best bets and picks, visit our interactive Darderi vs. Spizzirri predictions page.

Darderi vs. Spizzirri prediction: Who will win and advance to the Round of 32?

Using innovative machine learning and data analysis, we have simulated the result of Wednesday's Darderi-Spizzirri men's singles match 10,000 times as part of our tennis predictions coverage.

Our famous predictive model currently gives Darderi a 59% chance of winning against Spizzirri in the US Open 2025.

Additionally, Darderi has a 57% chance of winning the first set, while the under 38.5 games has a 54% chance of hitting, according to our model.

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Luciano Darderi vs. Eliot Spizzirri odds

We have sourced the most up-to-date betting odds in America for this match, which are listed here:

Bet Type	Darderi	Spizzirri
Moneyline	-150	+137
First Set	-152	+120
Total Games	o38.5 (-115)	u38.5 (-120)

All odds are correct at the time of publication and are subject to change.

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Darderi vs. Spizzirri picks and best bets

Our model's strongest edge in today's Darderi vs. Spizzirri match is on the first set.

Our expert predictions, matched against the latest odds, reveal the best tennis picks and tennis best bets for every tournament throughout the year.

Unlimited access to our complete suite of picks, including this one, is available via Dimers Pro.

Darderi vs. Spizzirri updates and essential details

The US Open 2025 match between Luciano Darderi and Eliot Spizzirri is scheduled to commence on Wednesday at 5:10PM ET.

• Who: Luciano Darderi vs. Eliot Spizzirri
• Date: Wednesday, August 27, 2025
• Approx. Time: 5:10PM ET/2:10PM PT
• Tournament: US Open Men's Singles 2025
• Round: Second round

All dates and times in this article are United States Eastern Time unless otherwise stated.

Dimers.com's in-depth preview of Wednesday's Darderi vs. Spizzirri match includes our prediction, picks and the latest betting odds.

Before making any Luciano Darderi vs. Eliot Spizzirri picks, be sure to check out the latest tennis predictions and betting advice from Dimers Pro.

Key tennis betting guides and insights

• Learn how to bet on tennis and understand how tennis odds work
• Explore where sports odds come from and how they’re applied to tennis matches
• Stay informed with guides on where online sports betting is currently legal and which states could legalize next
• Improve your chances with proven sports betting strategies that apply to tennis and more

Conclusion

We predict Luciano Darderi, with a 59% win probability, will likely beat Eliot Spizzirri at the US Open 2025.

AI and automation have enhanced this article to quickly deliver accurate Darderi vs. Spizzirri insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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