Louisville vs. Virginia Tech Prediction: Louisville Predicted to Win College Basketball Matchup [2/25/2025]

Virginia Tech and Louisville are scheduled to meet in college basketball action at Cassell Coliseum on Tuesday, with tipoff at 9:00PM ET.

Based on updated simulations, Dimers' proven college basketball model (see Dimers Pro for full access) projects Louisville as the most likely winner of today's game.

Check the latest March Madness bracket projections and 2025 NCAA Championship probabilities.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's Louisville-Virginia Tech game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various factors, our prediction shows Louisville with a win probability of 80%, compared to 20% for Virginia Tech."

For further insights into Tuesday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Louisville vs. Virginia Tech predictions page.

READER EXCLUSIVE: Use code 20BASKETBALL at checkout now to get 20% off your first month of Dimers Pro! Hurry, this offer won't last long.

Louisville vs. Virginia Tech Prediction: Who Will Win, Cover the Spread?

Using innovative machine learning and data analysis, we have simulated the outcome of Tuesday's NCAA basketball matchup between Louisville and Virginia Tech 10,000 times as part of our college basketball predictions coverage.

Our independent predictive model currently gives Louisville an 80% chance of defeating Virginia Tech. Our predicted final score has Louisville winning 76-67.

According to our model, Virginia Tech (+9.5) has a 55% chance of covering the spread, while the over/under total of 146.5 points has a 54% chance of staying under.

Louisville vs. Virginia Tech Odds

We have researched the best College Basketball odds in America for this game, which are listed here:

Bet Type	Louisville	Virginia Tech
Spread	-9.5 (-115)	+9.5 (-105)
Moneyline	-500	+440
Total	o146.5 (-115)	u146.5 (-105)

All odds are correct at the time of publication and are subject to change.

Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.

Louisville vs. Virginia Tech Picks and Best Bets

Our model's biggest edge in today's Louisville vs. Virginia Tech matchup is on the total.

Our expert predictions, matched against the current odds, reveal the best college basketball picks for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Louisville vs. Virginia Tech Game-Day Updates and Essential Details

Tuesday's college basketball action between Virginia Tech and Louisville at Cassell Coliseum is scheduled to start at 9:00PM ET.

• Who: Louisville vs. Virginia Tech
• Date: Tuesday, February 25, 2025
• Time: 9:00PM ET/6:00PM PT
• Venue: Cassell Coliseum

Dimers.com's comprehensive preview of Tuesday's Louisville vs. Virginia Tech matchup includes our prediction, picks and the latest betting odds.

Before making any Louisville vs. Virginia Tech picks, be sure to check out the latest college basketball predictions and betting advice from Dimers Pro.

Conclusion

We predict Louisville, with an 80% win probability, will likely beat Virginia Tech on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Louisville vs. Virginia Tech insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on College Basketball

Keep up with the latest college basketball news, college basketball best bets and CBB parlay picks throughout the season. Plus, our March Madness odds offer the most accurate probabilities for every March Madness contender.