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Louisville vs. Syracuse Prediction: Louisville Predicted to Win College Basketball Matchup [1/14/2025]

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Written by Dave Garofolo

Our expert prediction for Tuesday's Louisville vs Syracuse matchup.

Louisville-Syracuse Predictions and Game Preview.
JMA Wireless Dome sets the stage for the college basketball matchup between Louisville and Syracuse this Tuesday.

Syracuse and Louisville will meet in college basketball action at JMA Wireless Dome on Tuesday, with tipoff at 7:00PM ET.

Based on updated simulations, Dimers' proven college basketball model (see Dimers Pro for full access) projects Louisville as the most likely winner of today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's Louisville-Syracuse game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various factors, our prediction shows Louisville with a win probability of 74%, compared to 26% for Syracuse."

For expanded analysis of Tuesday's matchup, including the predicted score, best bets and an expanded look at the predicted final score, visit our interactive Louisville vs. Syracuse predictions page.

READER EXCLUSIVE: Use code 20BASKETBALL at checkout now to get 20% off your first month of Dimers Pro! Hurry, this offer won't last long.

Louisville vs. Syracuse Game-Day Updates and Essential Details

Tuesday's college basketball game between Syracuse and Louisville at JMA Wireless Dome is scheduled to commence at 7:00PM ET.

Dimers.com's in-depth preview of Tuesday's Louisville vs. Syracuse matchup includes our prediction, picks and the latest betting odds.

Before making any Louisville vs. Syracuse picks, be sure to check out the latest college basketball predictions and betting advice from Dimers Pro.

Louisville vs. Syracuse Prediction: Who Will Win, Cover the Spread?

Using powerful machine learning and statistical analysis, we have simulated the outcome of Tuesday's NCAA basketball matchup between Louisville and Syracuse 10,000 times as part of our college basketball predictions coverage.

Our leading predictive model gives Louisville a 74% chance of beating Syracuse. Our predicted final score has Louisville winning 79-72.

According to our model, Syracuse (+7.5) has a 55% chance of covering the spread, while the over/under total of 151.5 points has an equal 50-50 chance of hitting.

 

Louisville vs. Syracuse Odds

We have sourced the best betting odds in America for this game, which are listed here:

Bet Type Louisville Syracuse
Spread -7.5 (-115) +7.5 (-105)
Moneyline -350 +315
Total o151.5 (-115) u151.5 (-105)

All odds are correct at the time of publication and are subject to change.

Louisville vs. Syracuse Picks

Our model's strongest edge in today's Louisville vs. Syracuse matchup is on the total.

Our expert predictions, matched against the best odds, reveal the best college basketball picks for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Conclusion

We predict Louisville, with a 74% win probability, will likely beat Syracuse on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Louisville vs. Syracuse insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.

More on College Basketball

Stay up-to-date with the latest college basketball news, college basketball best bets and CBB parlay picks throughout the season. Plus, our March Madness odds offer the latest probabilities for every March Madness contender.

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Written by
Dave Garofolo
Content Producer

Dave Garofolo uses sophisticated AI-driven analytics to make predictions and evaluate player performances in the NBA, MLB, NFL, NHL, NCAAM, and PGA TOUR tournaments, crafting insightful game and prop previews.

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