Louisville vs. SMU Prediction: SMU Predicted to Win College Basketball Matchup [1/21/2025]

SMU will take on Louisville in college basketball action at Moody Coliseum on Tuesday, starting at 9:00PM ET.

Based on the latest simulations, Dimers' proven college basketball model (see Dimers Pro for full access) predicts SMU as the most likely winner of today's game.

"Our team has analyzed the latest data and conducted 10,000 simulations for Tuesday's Louisville-SMU game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various factors, our prediction shows SMU with a win probability of 55%, compared to 45% for Louisville."

For further insights into Tuesday's matchup, including the predicted score, best bets and an expanded look at the predicted final score, visit our interactive Louisville vs. SMU predictions page.

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Louisville vs. SMU Game-Day Updates and Essential Details

Tuesday's college basketball game between SMU and Louisville at Moody Coliseum is scheduled to start at 9:00PM ET.

• Who: Louisville vs. SMU
• Date: Tuesday, January 21, 2025
• Time: 9:00PM ET/6:00PM PT
• Venue: Moody Coliseum
• Tickets: Get tickets for the game on Ticketmaster

Dimers.com's in-depth preview of Tuesday's Louisville vs. SMU matchup includes our prediction, picks and the latest betting odds.

Before making any Louisville vs. SMU picks, be sure to check out the latest college basketball predictions and betting advice from Dimers Pro.

Louisville vs. SMU Prediction: Who Will Win, Cover the Spread?

Using innovative machine learning and data analysis, we have simulated the outcome of Tuesday's NCAA basketball matchup between Louisville and SMU 10,000 times as part of our college basketball predictions coverage.

Our leading predictive model gives SMU a 55% chance of beating Louisville. Our predicted final score has SMU winning 79-77.

According to our model, Louisville (+1.5) has a 53% chance of covering the spread, while the over/under total of 159 points has a 52% chance of staying under.

Louisville vs. SMU Odds

We have sourced the best betting odds in America for this game, which are listed here:

Bet Type	Louisville	SMU
Spread	+1.5 (-102)	-1.5 (-115)
Moneyline	+115	-132
Total	o159 (-112)	u159 (-108)

All odds are correct at the time of publication and are subject to change.

Louisville vs. SMU Picks

Our model's biggest edge in today's Louisville vs. SMU matchup is on the over/under.

Our expert predictions, matched against the latest odds, reveal the best college basketball picks for every game throughout the season.

Unlimited access to our complete set of picks, including this one, is available via Dimers Pro.

Conclusion

We predict SMU, with a 55% win probability, will likely beat Louisville on Tuesday.

AI and automation have enhanced this article to quickly deliver accurate Louisville vs. SMU insights, with human oversight ensuring high editorial quality. Our predictions are based on the latest data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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