College Basketball- More Betting
Louisville vs. Notre Dame Prediction: Louisville Predicted to Win College Basketball Matchup [2/16/2025]
Our expert prediction for Sunday's Louisville vs Notre Dame matchup.

College basketball action continues on Sunday at 8:00PM ET as the favored Louisville squares off with Notre Dame in college basketball action at Purcell Pavilion.
Based on updated simulations, Dimers' proven college basketball model (see Dimers Pro for full access) projects Louisville as the most likely winner of today's game.
"Using the most recent data, our experts ran 10,000 simulations of Sunday's Louisville-Notre Dame game," said Dimers' Chief Content Officer, Nick Slade.
"After accounting for recent updates and other variables, our prediction shows Louisville with a win probability of 73%, while Notre Dame has 27%."
For expanded analysis of Sunday's matchup, including the predicted score, best bets and an expanded look at the predicted final score, visit our interactive Louisville vs. Notre Dame predictions page.
NEW OFFER: Sign up to Dimers Pro for $9.99 a week and enjoy flexibiilty at its best.
Louisville vs. Notre Dame Prediction: Who Will Win, Cover the Spread?
Using innovative machine learning and data analysis, we have simulated the result of Sunday's NCAA basketball matchup between Louisville and Notre Dame 10,000 times as part of our college basketball predictions coverage.
Our famous predictive model currently gives Louisville a 73% chance of beating Notre Dame. Our predicted final score has Louisville winning 75-69.
According to our model, Notre Dame (+7.5) has a 55% chance of covering the spread, while the over/under total of 147.5 points has a 54% chance of staying under.
Louisville vs. Notre Dame Odds
We have researched the best College Basketball odds in America for this game, which are listed here:
Bet Type | Louisville | Notre Dame |
---|---|---|
Spread | -7.5 (-110) | +7.5 (-105) |
Moneyline | -315 | +280 |
Total | o147.5 (-115) | u147.5 (-105) |
All odds are correct at the time of publication and are subject to change.
Make the most of your sports betting experience by exploring our comprehensive list of US betting apps, and the latest sportsbooks in 2025, ensuring you never miss a top new-user deal.
Louisville vs. Notre Dame Picks and Best Bets
Our model's biggest edge in today's Louisville vs. Notre Dame matchup is on the over/under.
Our expert predictions, aligned with the best odds, reveal the best college basketball picks for every game throughout the season.
Unlimited access to our full set of picks, including this one, is available via Dimers Pro.
Louisville vs. Notre Dame Game-Day Updates and Essential Details
Sunday's college basketball matchup between Notre Dame and Louisville at Purcell Pavilion is scheduled to commence at 8:00PM ET.
- Who: Louisville vs. Notre Dame
- Date: Sunday, February 16, 2025
- Time: 8:00PM ET/5:00PM PT
- Venue: Purcell Pavilion
Dimers.com's comprehensive preview of Sunday's Louisville vs. Notre Dame matchup includes our prediction, picks and the latest betting odds.
Before making any Louisville vs. Notre Dame picks, be sure to check out the latest college basketball predictions and betting advice from Dimers Pro.
Sports Betting Deals Available for Sunday
To make the most of Sunday's massive day of sports, headlined by the final round of play at the Genesis Invitational and the NBA All-Star game, check out details on the latest Bet365 bonus code "DIMERS" that unlocks the choice of two outstanding signup promotions. Don't miss out!
Conclusion
We predict Louisville, with a 73% win probability, will likely beat Notre Dame on Sunday.
AI and automation have enhanced this article to quickly deliver accurate Louisville vs. Notre Dame insights, with human oversight ensuring high editorial quality. Our predictions are sourced from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.
Note: Clicking links to our partners may earn us a referral fee. Learn about how we review products and services.
More on College Basketball
Keep up with the latest college basketball betting news, college basketball best bets and CBB parlay picks throughout the season. Plus, our March Madness odds provide the latest probabilities for every March Madness contender.