Louisiana-Lafayette vs. Southern Miss Prediction: Southern Miss Predicted to Win College Basketball Matchup [2/22/2025]

Southern Miss will face Louisiana-Lafayette in college basketball action at Reed Green Coliseum on Saturday, starting at 8:00PM ET.

Based on the latest simulations, Dimers' advanced college basketball model (see Dimers Pro for full access) predicts Southern Miss as the most likely winner of today's game.

Check the latest March Madness bracket projections and 2025 NCAA Championship probabilities.

"Our team has used the latest data to run 10,000 simulations of Saturday's Louisiana-Lafayette-Southern Miss game," said Dimers' Chief Content Officer, Nick Slade.

"By incorporating recent updates and various other inputs, we estimate that Southern Miss is more likely to win, while Louisiana-Lafayette has a lower chance of victory."

For expanded analysis of Saturday's matchup, including an expanded look at the predicted score, best bets and picks, visit our interactive Louisiana-Lafayette vs. Southern Miss predictions page.

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Louisiana-Lafayette vs. Southern Miss Prediction: Who Will Win, Cover the Spread?

Using trusted machine learning and data, we have simulated the result of Saturday's NCAA basketball matchup between Louisiana-Lafayette and Southern Miss 10,000 times as part of our college basketball predictions coverage.

Our leading predictive model currently gives Southern Miss a 64% chance of defeating Louisiana-Lafayette. Our predicted final score has Southern Miss winning 76-72.

According to our model, Louisiana-Lafayette (+4.5) has a 55% chance of covering the spread, while the 148.5-point over/under has an equal 50-50 chance of hitting.

Louisiana-Lafayette vs. Southern Miss Odds

We have researched the best College Basketball odds in America for this game, which are listed here:

Bet Type	Louisiana-Lafayette	Southern Miss
Spread	+4.5 (-114)	-4.5 (-105)
Moneyline	+160	-185
Total	o148.5 (-108)	u148.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Louisiana-Lafayette vs. Southern Miss Picks and Best Bets

Our model's biggest edge in today's Louisiana-Lafayette vs. Southern Miss matchup is on the total.

Our expert predictions, aligned with the current odds, reveal the best college basketball picks for every game throughout the season.

Unlimited access to our full set of picks, including this one, is available via Dimers Pro.

Louisiana-Lafayette vs. Southern Miss Game-Day Updates and Essential Details

Saturday's college basketball matchup between Southern Miss and Louisiana-Lafayette at Reed Green Coliseum is scheduled to begin at 8:00PM ET.

• Who: Louisiana-Lafayette vs. Southern Miss
• Date: Saturday, February 22, 2025
• Time: 8:00PM ET/5:00PM PT
• Venue: Reed Green Coliseum

Dimers.com's full preview of Saturday's Louisiana-Lafayette vs. Southern Miss matchup includes our prediction, picks and the latest betting odds.

Before making any Louisiana-Lafayette vs. Southern Miss picks, be sure to check out the latest college basketball predictions and betting advice from Dimers Pro.

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Conclusion

We predict Southern Miss, with a 64% win probability, will likely beat Louisiana-Lafayette on Saturday.

AI and automation have enhanced this article to quickly deliver accurate Louisiana-Lafayette vs. Southern Miss insights, with human oversight ensuring high editorial quality. Our predictions are drawn from up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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