Rams vs. Titans prediction: Why Rams are favored to win in NFL Week 2, 2025

The Tennessee Titans will square off with the favored Los Angeles Rams in NFL Week 2 action at Nissan Stadium on Sunday, starting at 1:00PM ET.

Based on updated simulations, Dimers' proven NFL model predicts the Rams as the most likely winner of today's game.

"Using the most recent data, our experts ran 10,000 simulations of Sunday's Rams-Titans game," said Dimers' Chief Content Officer, Nick Slade.

"After accounting for recent updates and other variables, our prediction shows the Rams with a win probability of 70%, while the Titans have 30%."

This gameday Rams vs. Titans betting preview builds on my Rams vs. Titans prediction that was published earlier in the week.

For a closer look at today’s game, including the predicted score, best bets and player prop picks, visit our interactive Rams vs. Titans predictions page.

Rams vs. Titans Predictions

Since our Rams-Titans predictions earlier in the week, we have simulated the outcome of Sunday's NFL matchup between the Rams and Titans 10,000 times as part of our NFL predictions coverage.

Our famous predictive model gives the Rams a 70% chance of beating the Titans in Week 2 of the NFL season. Our predicted final score has the Rams winning 23-18.

According to our model, the Titans (+5.5) have a 54% chance of covering the spread, while the 40.5-point over/under has a 53% chance of going over.

Rams vs. Titans odds

We have sourced the best NFL odds in America for this game, which are listed here:

Bet Type	Rams	Titans
Spread	-5.5 (-108)	+5.5 (-105)
Moneyline	-250	+210
Total	o40.5 (-115)	u40.5 (-105)

All odds are correct at the time of publication and are subject to change.

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Rams vs. Titans picks and best bets

Our model's biggest edge in today's Rams vs. Titans matchup is on the over/under.

Our expert predictions, matched against the best odds, reveal the best NFL picks and NFL best bets for every game throughout the season.

Unlimited access to our full suite of picks, including this one, is available via Dimers Pro.

Rams vs. Titans TD scorers

Who will score the first touchdown in Rams vs. Titans?

According to our model, Los Angeles' Kyren Williams is most likely to score the first TD in Rams vs. Titans.

Our projections give Williams an 18.1% chance of getting in for six first at Nissan Stadium, while the Rams running back is a 58.9% chance of reaching the end zone at any point during the game.

First touchdown scorer predictions

Los Angeles Rams

Player	First TD Probability
Kyren Williams (RB)	18.1%
Davante Adams (WR)	9.1%
Puka Nacua (WR)	8.9%

Tennessee Titans

Player	First TD Probability
Tony Pollard (RB)	13.3%
Calvin Ridley (WR)	7.7%
Elic Ayomanor (WR)	5.0%

Anytime touchdown scorer predictions

Los Angeles Rams

Player	Anytime TD Probability
Kyren Williams (RB)	58.9%
Davante Adams (WR)	36.1%
Puka Nacua (WR)	35.4%

Tennessee Titans

Player	Anytime TD Probability
Tony Pollard (RB)	42.5%
Calvin Ridley (WR)	27.6%
Elic Ayomanor (WR)	18.8%

Rams vs Titans player props

Discover our predictions for the players likely to lead in passing, rushing and receiving yards for both the Rams and Titans. For detailed projections, join Dimers Pro.

Already a Dimers Pro member? Head to our Rams-Titans page now to access every player prop projection.

Rams vs. Titans quarterbacks

Of the starting quarterbacks, the Rams' Matthew Stafford is projected to throw for more yards than the Titans' Cam Ward.

Rams rushing

Kyren Williams, Blake Corum and Matthew Stafford are projected to be the leading rushers for the Rams.

Player	Position
Kyren Williams	RB
Blake Corum	RB
Matthew Stafford	QB

Titans rushing

Tony Pollard, Cam Ward and Julius Chestnut are expected to lead the Titans in rushing yards.

Player	Position
Tony Pollard	RB
Cam Ward	QB
Julius Chestnut	RB

Rams receiving

Puka Nacua, Davante Adams, Tutu Atwell, Tyler Higbee and Kyren Williams are projected to top the receiving yards for the Rams.

Player	Position
Puka Nacua	WR
Davante Adams	WR
Tutu Atwell	WR
Tyler Higbee	TE
Kyren Williams	RB

Titans receiving

Calvin Ridley, Elic Ayomanor, Chig Okonkwo, Tyler Lockett and Tony Pollard are projected to lead the Titans in receiving yards.

Player	Position
Calvin Ridley	WR
Elic Ayomanor	WR
Chig Okonkwo	TE
Tyler Lockett	WR
Tony Pollard	RB

Rams vs. Titans game-day updates and essential details

The NFL Week 2 game between the Titans and Rams at Nissan Stadium is scheduled to begin at 1:00PM ET.

• Who: Los Angeles Rams vs. Tennessee Titans
• Date: Sunday, September 14, 2025
• Time: 1:00PM ET/10:00AM PT
• Venue: Nissan Stadium

Dimers' in-depth preview of this week's Rams vs. Titans matchup includes our prediction, picks and the latest betting odds.

Before making any Rams vs. Titans picks, be sure to check out the latest NFL predictions and betting advice from Dimers Pro.

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Conclusion

We predict the Rams, with a 70% win probability, will likely beat the Titans in Week 2 of the NFL season.

AI and automation have enhanced this article to quickly deliver accurate Rams vs. Titans insights, with human oversight ensuring high editorial quality. Our predictions are based on up-to-date data to help you make informed decisions. For additional resources and advice on responsible gambling, please call 1-800-GAMBLER.

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